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Heat shock factor 1 represses estrogen-dependent transcription through association with MTA1
(Nature Publishing Group, 2008-03)
Heat shock factor 1 (HSF1), the transcriptional activator of the heat shock genes, is increasingly implicated in cancer. We have shown that HSF1 binds to the corepressor metastasis-associated protein 1 (MTA1) in vitro and ...
Effects of chlorogenic acid on thermal stress tolerance in C. elegans via HIF-1, HSF-1 and autophagy
(Elsevier Gmbh, 2020-01)
Chlorogenic acid (CGA) is a polyphenol widely distributed in plants and plant-derived food with antioxidant and protective activities against cell stress. Caenorhabditis elegans is a model organism particularly useful for ...
Regulatory motifs found in the small heat shock protein (sHSP) gene family in tomato
(BioMed Central, 2018-12)
Background: In living organisms, small heat shock proteins (sHSPs) are triggered in response to stress situations. This family of proteins is large in plants and, in the case of tomato (Solanum lycopersicum), 33 genes have ...
Regulatory role of heat-shock proteins in autoimmune and inflammatory diseases
(Open Access Text, 2016-08-22)
Classically, molecular chaperones play a pivotal role in the maintenance of cellular proteostasis and thus, in the safeguarding of the cell homeostasis while reducing the deleterious effects of extracellular and intracellular ...
Small heat shock proteins and the postharvest chilling tolerance of tomato fruit
(Wiley Blackwell Publishing, Inc, 2017-02)
Plants have the largest number of small heat shock proteins (sHsps) (15–42 kDa) among eukaryotes, but little is known about their function in vivo. They accumulate in response to different stresses, and specific sHsps are ...
Correlação da imunoexpressão do fator de choque térmico 1 (hsf1) com aspectos clinicopatológicos em carcinomas de células escamosas de língua oral
(Universidade Federal do Rio Grande do NorteBrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM PATOLOGIA ORAL, 2016-02-26)
Squamous cell carcinoma of oral tongue shows high rates of morbidity and mortality in the population, therefore, great efforts are being made to classify morphological changes and identify biomarkers that have prognostic ...
Análise da forma fosforilada do fator de choque térmico 1 (pHSF 1) em carcinomas de células escamosas de língua oral
(BrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM PATOLOGIA ORAL, 2018-01-29)
The squamous cell carcinoma (SCC) of the oral tongue presents morbimortality high levels although recent achievements of malignancies treatment. This way, a lot of researches are trying to detect morphological alterations ...