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Mostrando ítems 11-20 de 102
Evaluation of humoral and cellular immune response after heterologous prime-boost immunization against SARS-CoV-2
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2021)
Leukotrienes are not essential for the efficacy of a heterologous vaccine against Mycobacterium tuberculosis infection
(Associação Brasileira de Divulgação Científica (ABRADIC), 2014)
IFN-γ-induced priming maintains long-term strain-transcending immunity against blood-stage Plasmodium chabaudi malaria
(American Association of ImmunologistsBaltimore, 2013-11-15)
The mechanism by which protective immunity to Plasmodium is lost in the absence of continued exposure to this parasite has yet to be fully elucidated. It has been recently shown that IFN-γ produced during human and murine ...
Perforin and Gamma Interferon Expression Are Required for CD4(+) and CD8(+) T-Cell-Dependent Protective Immunity against a Human Parasite, Trypanosoma cruzi, Elicited by Heterologous Plasmid DNA Prime-Recombinant Adenovirus 5 Boost Vaccination
(Amer Soc Microbiology, 2009-10-01)
A heterologous prime-boost strategy using plasmid DNA, followed by replication-defective recombinant adenovirus 5, is being proposed as a powerful way to elicit CD4(+) and CD8(+) T-cell-mediated protective immunity against ...
Protection conferred by heterologous vaccination against tuberculosis is dependent on the ratio of CD4(+)/CD4(+) Foxp3(+) cells
(WILEY-BLACKWELLHOBOKEN, 2012)
CD4(+) Foxp3(+) regulatory T cells inhibit the production of interferon-?, which is the major mediator of protection against Mycobacterium tuberculosis infection. In this study, we evaluated whether the protection conferred ...
Mucosal Heterologous Prime/Boost Vaccination Induces Polyfunctional Systemic Immunity, Improving Protection Against Trypanosoma cruzi
(Frontiers Research Foundation, 2020-02)
There are several unmet needs in modern immunology. Among them, vaccines against parasitic diseases and chronic infections lead. Trypanosoma cruzi, the causative agent of Chagas disease, is an excellent example of a silent ...
Imunogenicidade de diferentes candidatos e estratégias vacinais para os vírus Zika e Chikungunya
(Universidade Federal de São Paulo (UNIFESP), 2021)
Arbovirus infections such as those caused by Zika virus (ZIKV) and Chikungunya virus (CHIKV) are responsible for a large number of cases with considerable severity and morbidity. So far, there are no vaccines or specific ...