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Metabolic and Inflammatory Adaptation of Reactive Astrocytes: Role of PPARs
(Humana Press Inc., 2017)
Quercetin ameliorates glucose and lipid metabolism and improves antioxidant status in postnatally monosodium glutamate-induced metabolic alterations
(Pergamon-Elsevier Science LtdOxford, 2012)
Effects of Perinatal Fluoride Exposure on Short- and Long-Term Memory, Brain Antioxidant Status, and Glutamate Metabolism of Young Rat Pups
(SAGE Publications, 2019-06)
Exposure to fluoride (F) during the development affects central nervous system of the offspring rats which results in theimpairment of cognitive functions. However, the exact mechanisms of F neurotoxicity are not clearly ...
Glutamate Induces Apoptosis in Anterior Pituitary Cells through Group II Metabotropic Glutamate Receptor Activation
(Endocrine Society, 2004-10)
Glutamate can induce neuronal cell death by activating ionotropic glutamate receptors (iGluRs) as well as metabotropic glutamate receptors (mGluRs). In the present study, we investigated whether glutamate induces apoptosis ...
Alcohol hangover induces nitric oxide metabolism changes by impairing NMDA receptor-PSD95-nNOS pathway
(Academic Press Inc Elsevier Science, 2021-09)
Alcohol hangover is defined as the combination of mental and physical symptoms experienced the day after a single episode of heavy drinking, starting when blood alcohol concentration approaches zero. We previously evidenced ...
Iron and glutathione at the crossroad of redox metabolism in neurons
(Sociedad de Biología de Chile, 2006)
Obesity induced by neonatal treatment with monosodium glutamate impairs microvascular reactivity in adult rats: Role of NO and prostanoids
(ELSEVIER SCI LTD, 2011)
Background and aim: given that obesity is an independent risk factor for the development of cardiovascular diseases we decided to investigate the mechanisms involved in microvascular dysfunction using a monosodium glutamate ...
Raloxifene attenuates oxidative stress and preserves mitochondrial function in astrocytic cells upon glucose deprivation
(Facultad de Ciencias de la Salud, 2019)
Oxidative stress and mitochondrial dysfunction induced by metabolic insults are both hallmarks of various neurological disorders, whereby neuronal cells are severely affected by decreased glucose supply to the brain. Likely ...
Metabolic changes following perinatal Asphyxia: Role of astrocytes and their interaction with neurons
(Frontiers Research Foundation, 2016)