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Coevolution of an aminoacyl-tRNA synthetase with its tRNA substrates
(NATL ACAD SCIENCES, 2003-11-25)
Glutamyl-tRNA synthetases (GluRSs) occur in two types, the discriminating and the nondiscriminating enzymes. They differ in their choice of substrates and use either tRNA(Glu) or both tRNA(Glu) and tRNA(Gln). Although most ...
The Helicobacter pylori amidotransferase GatCAB is equally efficient in glutamine-dependent transamidation of Asp-tRNAAsn and Glu-tRNA Gln
(2007)
The amide aminoacyl-tRNAs, Gln-tRNAGln and Asn-tRNA Ans, are formed in many bacteria by a pretranslational tRNA-dependent amidation of the mischarged tRNA species, GlutRNAGln or Asp-tRNAAsn. This conversion is catalyzed ...
Gln(27)-> Glu beta(2)-Adrenergic Receptor Polymorphism in Heart Failure Patients: Differential Clinical and Oxidative Response to Carvedilol
(WILEY-BLACKWELL PUBLISHING, 2009-05)
We investigated the clinical response of chronic heart failure patients with beta(2)- adrenergic receptor Gln(27)-> Glu polymorphism treated for 6 months with carvedilol, a alpha/beta-antagonist with antioxidant properties. ...