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Human leukocyte antigens and malignant essential hypertension
(Elsevier B.V., 1998-06-01)
The purpose of this study was to investigate an association between human leukocyte antigens (HLA) and the susceptibility to malignant hypertension. the presence of HLA-A -B, -DR, and -DQ was determined in 33 white and in ...
An update on the pharmacogenetics of treating hypertension
(Nature Publishing Group, 2015-05-01)
Hypertension is a leading cause of cardiovascular mortality, but only one third of patients achieve blood pressure goals despite antihypertensive therapy. Genetic polymorphisms may partially account for the interindividual ...
Does Renal Denervation Fit All Resistant Hypertension? The Role Of Genetics
(WILEY-BLACKWELLHOBOKEN, 2016)
Association between endothelial nitric oxide synthase and the renin-angiotensin-aldosterone system polymorphisms, blood pressure and training status in normotensive/pre-hypertension and hypertensive older adults: a pilot study
(2021-01-01)
Introduction:Variations in blood pressure (BP) are, in part, genetically determined and some polymorphisms of renin-angiotensin- aldosterone system (RAAS) and synthase of endothelial nitric oxide (eNOS) have been related ...
Alterations in Angiotensin and Atrial Natriuretic Peptide Receptors in Brain Nuclei of Spontaneously Hypertensive Rats
(Journal of Hypertension, 2011)
Plasmatic biochemical variables associated with polymorphisms in the endothelin-1 and endothelin-1 receptor a genes in hypertensive patients : pilot study
(2016)
Aims: Endothelin-1 (ET-1) is a potent vasoconstrictive peptide, and its activity is mediated by the type A receptor (EDNRA). This action may play a significant role in the etiology of hypertension. There are different works ...