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Yeast-based assay identifies novel Shh/Gli target genes in vertebrate development
(BIOMED CENTRAL LTD, 2012-01-03)
Background: The increasing number of developmental events and molecular mechanisms associated with the Hedgehog (Hh) pathway from Drosophila to vertebrates, suggest that gene regulation is crucial for diverse cellular ...
Influence of aluminum oxide on the prebiotic thermal synthesis of Gly-Glu-(Gly-Glu)n polymer
(2011)
The effect of the aluminum oxide on the thermal synthesis of the glycine-glutamic acid (Gly-Glu-(Gly-Glu)n polymer is described. The thermal synthesis in the molten state was carried out in the absence and presence of the ...
Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex
(2004)
Stem cells are crucial for normal development and homeostasis, and their misbehavior may be related to the origin of cancer. Progress in these areas has been difficult because the mechanisms regulating stem cell lineages ...
Tamoxifen treatment of breast cancer cells : Impact on Hedgehog/GLI1 signaling
(2016)
The selective estrogen receptor (ER) modulator tamoxifen (TAM) has become the standard therapy for the treatment of ER+ breast cancer patients. Despite the obvious benefits of TAM, a proportion of patients acquire resistance ...
Sonic hedgehog (Shh)/Gli modulates the spatial organization of neuroepithelial cell proliferation in the developing chick optic tectum
(2012)
Background: Sonic hedgehog (Shh)/Gli pathway plays an important regulatory role on the neuroepithelial cells (NEc) proliferation in the dorsal regions of the developing vertebrate Central Nervous System. The aim of this ...
The period gene Thr-Gly polymorphism in Australian and African Drosophila melanogaster populations: implications for selection
(Genetics Society of America, 2020)
Leucine and tissue distribution of bulky and small neutral amino acids in rats: dissociation between transport and insulin-mediated effects
(1992)
The mechanism of the observed decrease in the plasma concentration of several amino acids in the presence of high levels of Leu has remained unexplained. In the present study a decrease in the plasma concentration of Ile, ...
Leucine and tissue distribution of bulky and small neutral amino acids in rats: dissociation between transport and insulin-mediated effects
(1992)
The mechanism of the observed decrease in the plasma concentration of several amino acids in the presence of high levels of Leu has remained unexplained. In the present study a decrease in the plasma concentration of Ile, ...
Gli2 is required for the induction and migration of Xenopus laevis neural crest
(Elsevier, 2018-08)
The neural crest (NC) is a multipotent migratory embryonic population that is formed during late gastrulation and gives rise to a wide array of derivatives, including cells from the peripheral nervous system (PNS), the ...