Buscar
Mostrando ítems 11-20 de 92
Intrinsically Disordered Regions of the DNABinding Domain of Human FoxP1 Facilitate Domain Swapping
(Elsevier, 2020)
Forkhead box P (FoxP) proteins are unique transcription factors that spatiotemporally regulate gene expression by
tethering two chromosome loci together via functional domain-swapped dimers formed through their ...
The forkhead-box family of transcription factors: Key molecular players in colorectal cancer pathogenesis 06 Biological Sciences 0604 Genetics 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis 06 Biological Sciences 0601 Biochemistry and Cell Biology
Colorectal cancer (CRC) is the third most commonly occurring cancer worldwide and the fourth most frequent cause of death having an oncological origin. It has been found that transcription factors (TF) dysregulation, leading ...
Forkhead box O1 (FOXO1) protein, but not p53, contributes to robust induction of p21 expression in fasted mice
(American Society for Biochemistry and Molecular Biology, 2013-09)
Reporter mice that enable the activity of the endogenous p21 promoter to be dynamically monitored in real time in vivo and under a variety of experimental conditions revealed ubiquitous p21 expression in mouse organs ...
Population, Epidemiological, and Functional Genetics of Gastric Cancer Candidate Genes in Peruvians with Predominant Amerindian Ancestry
(Springer, 2015)
Background. Gastric adenocarcinoma is associated with chronic infection by Helicobacter pylori and with the host inflammatory response triggered by it, with substantial inter-person variation in the immune response profile ...
rs2802292 polymorphism in the FOXO3A gene and exceptional longevity in two ethnically distinct cohorts
(Elsevier Ireland Ltd, 2016)
The multisystemic functions of FOXD1 in development and disease
Transcription factors (TFs) participate in a wide range of cellular processes due to their inherent function as essential regulatory proteins. Their dysfunction has been linked to numerous human diseases. The forkhead box ...