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Iron supply determines apical/basolateral membrane distribution of intestinal iron transporters DMT1 and ferroportin 1
(2010)
00168.2009.—Intestinal iron absorption comprises
the coordinated activity of the influx transporter divalent metal
transporter 1 (DMT1) and the efflux transporter ferroportin (FPN). In
this work, we studied the movement ...
Calcium and zinc decrease intracellular iron by decreasing transport during iron repletion in an in vitro model
(2017)
Abstract . Purpose Iron is an essential micronutrient that participates in a number of vital reactions and its absorption may be altered by various nutritional factors such as other micronutrients. Our hypothesis is that ...
Immunohistochemical studies on duodenum, spleen and liver in mice: Distribution of ferroportin and prohepcidin in an inflammation modelEstudios inmunohistoquímicos en duodeno, bazo e hígado de ratón: Distribución de ferroportina y prohepcidina en un modelo de inflamación
(Sociedad Chilena de Anatomía, 2011-09)
Duodenum, spleen and liver have a crucial role in iron balance on the whole organism and are the major sites of Ferroportin (FPN) expression. Specific regulations between FPN and hepcidin are responsible for changes seen ...
Adaptation of iron requirement to hypoxic conditions at high altitude
(American Physiological Society, 2015)
Adequate acclimatization time to enable adjustment to hypoxic conditions is one of the most important aspects for mountaineers ascending to high altitude. Accordingly, most reviews emphasize mechanisms that cope with reduced ...
Liver iron modulates hepcidin expression during chronically elevated erythropoiesis in mice
(Wiley, 2013)
The liver-derived peptide hepcidin controls the balance between iron demand and iron supply. By inhibiting the iron export activity of ferroportin, hepcidin modulates iron absorption and delivery from the body's stores. ...
Erythropoietin's inhibiting impact on hepcidin expression occurs indirectly
(American Physiological Society, 2015)
Under conditions of accelerated erythropoiesis, elevated erythropoietin (Epo) levels are associated with inhibition of hepcidin synthesis, a response that ultimately increases iron availability to meet the enhanced iron ...
Erythropoietin's inhibiting impact on hepcidin expression occurs indirectly
(American Physiological Society, 2015)
Under conditions of accelerated erythropoiesis, elevated erythropoietin (Epo) levels are associated with inhibition of hepcidin synthesis, a response that ultimately increases iron availability to meet the enhanced iron ...
Increased hepcidin expression in multibacillary leprosy
(FUNDACO OSWALDO CRUZRIO DE JANEIRO, RJ, 2012)
Iron is essential for all organisms and its availability can control the growth of microorganisms; therefore, we examined the role of iron metabolism in multibacillary (MB) leprosy, focusing on the involvement of hepcidin. ...