Buscar
Mostrando ítems 11-20 de 859
Ascl1 Balances Neuronal versus Ependymal Fate in the Spinal Cord Central Canal
(Elsevier, 2019-08)
Generation of neuronal types at the right time, location, and number is essential for building a functional nervous system. Significant progress has been reached in understanding the mechanisms that govern neuronal diversity. ...
Granulocyte-Colony Stimulating Factor (G-CSF) induces mechanical hyperalgesia via spinal activation of MAP kinases and PI(3)K in mice
(PERGAMON-ELSEVIER SCIENCE LTD, 2011)
Granulocyte-colony stimulating factor (G-CSF) is a current pharmacological approach to increase peripheral neutrophil counts after anti-tumor therapies. Pain is most relevant side effect of G-CSF in healthy volunteers and ...
M-CSF Priming of Osteoclast Precursors Can Cause Osteoclastogenesis-Insensitivity, Which Can be Prevented and Overcome on Bone
(Wiley-Blackwell, 2015-01-01)
Osteoclasts and macrophages share progenitors that must receive decisive lineage signals driving them into their respective differentiation routes. Macrophage colony stimulation factor M-CSF is a common factor; bone is ...
The granulocyte colony stimulating factor (G-CSF) activates Jak/STAT and MAPK pathways in a trophoblastic cell line
(Wiley-liss, div John Wiley & Sons Inc., 2008-02)
Granulocyte colony-stimulating factor receptor (G-CSFR) has been found in placenta tissues, although its functional role has not yet been defined. In order to explore the molecular pathways induced by G-CSF in this tissue, ...
Uso do estimulante de colônia de granulócitos nas neutropenias em cães e gatos
(Universidade Federal de Santa Maria (UFSM), 2007-06-01)
As neutropenias persistentes podem ser decorrentes de alterações na granulopoiese, causadas por efeitos supressivos ou tóxicos à medula óssea, predispõem o paciente a infecções comprometendo sua sobrevida. As neutropenias ...
Recombinant human granulocyte-macrophage colony-stimulating factor: effect of glycosylation on pharmacokinetic parameters
(Pontificia Universidad Católica de Valparaíso, 2007)
Effect of thrombopoietin and granulocyte colony-stimulating factor on platelets and polymorphonuclear leukocytes
(Pergamon-Elsevier Science Ltd, 2000-07)
Thrombopoietin (TPO) and granulocyte colony-stimulating factor (G-CSF) may be administered together in aplastic patients. We evaluated the effect of both cytokines alone or combined on platelets and polymorphonuclear ...
Use of rhu-GM-CSF in pulmonary tuberculosis patients: results of a randomized clinical trial
(The Brazilian Journal of Infectious Diseases and Contexto Publishing, 2003-08)
It has been postulated that deficient or incomplete clinical and/or microbiological response to tuberculosis treatment is associated with cell-mediated immunological dysfunction involving monocytes and macrophages. A phase ...
Recovery of pulmonary structure and exercise capacity by treatment with granulocyte-colony stimulating factor (G-CSF) in a mouse model of emphysema
(2013-04-26)
Emphysema is a chronic obstructive pulmonary disease characterized abnormal dilatation of alveolar spaces, which impairs alveolar gas exchange, compromising the physical capacity of a patient due to airflow limitations. ...