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Mostrando ítems 11-20 de 436
The Immune Epitope Database and Analysis Resource Program 2003–2018: reflections and outlook
(Springer, 2019-11)
The Immune Epitope Database and Analysis Resource (IEDB) contains information related to antibodies and T cells across an expansive scope of research fields (infectious diseases, allergy, autoimmunity, and transplantation). ...
Characterization of binding specificities of bovine leucocyte class I molecules: impacts for rational epitope discovery
(Springer Heidelberg, 2014-12)
The binding of peptides to classical major histocompatibility complex (MHC) class I proteins is the single most selective step in antigen presentation. However, the peptide-binding specificity of cattle MHC (bovine leucocyte ...
PTML Model for proteom Mining of B-cell Epitopes and Theoretic-Experimental Study of Bm86 Sequences from Colima Mexico
(Journal of Proteome Research, 2018)
Development of bióinformatics tools to analyse peptide-protein interactións: immunoinformatics applicatións in next generatión vaccine design
(2017)
Epitope-based vaccines (EVs) make use of short, antigen-derived peptides corresponding
to epitopes that are administered lo trigger a protective humoral (B-cell epitopes) and/or
cellular (T-cell epitopes) immune response. ...
QSPR-Perturbation Models for the Prediction of B-Epitopes from Immune Epitope Database: A Potentially Valuable Route for Predicting “In Silico” New Optimal Peptide Sequences and/or Boundary Conditions for Vaccine Development
(Springer, 2016-12)
In the present study, three different physicochemical molecular properties for peptides were calculated using the program MARCH-INSIDE: atomic polarizability, partition coefficient, and polarity. These measures were used ...
NetTepi: an integrated method for the prediction of T-cell epitopes
(Springer Verlag Berlín, 2014-08)
Multiple factors determine the ability of a peptide to elicit a cytotoxic T cell lymphocyte response. Binding to a major histocompatibility complex class I (MHC-I) molecule is one of the most essential factors, as no peptide ...
Benchmarking predictions of MHC class I restricted T cell epitopes in a comprehensively studied model system
(Public Library of Science, 2020-05)
T cell epitope candidates are commonly identified using computational prediction tools in order to enable applications such as vaccine design, cancer neoantigen identification, development of diagnostics and removal of ...
PREDIVAC : CD4+ T-cell epitope prediction for vaccine design that covers 95% of HLA class II DR protein diversity
(2013-02-14)
Background: CD4+ T-cell epitopes play a crucial role in eliciting vigorous protective immune responses during peptide (epitope)-based vaccination. The prediction of these epitopes focuses on the peptide binding process by ...
An assessment on epitope prediction methods for protozoa genomes
(BioMed Central, 2014)
Determination of a predictive cleavage motif for eluted major histocompatibility complex class II ligands
(Frontiers Media S.A., 2018-08)
CD4+ T cells have a major role in regulating immune responses. They are activated by recognition of peptides mostly generated from exogenous antigens through the major histocompatibility complex (MHC) class II pathway. ...