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Tomato epigenetics: Deciphering the beyond genetic information in a vegetable fleshy-fruited crop
(2014-07-01)
The first natural plant mutant for which the molecular basis was determined to be an epimutation rather than a change in DNA sequence was a peloric variant of toadflax, Linaria vulgaris. Remarkably, the second example of ...
Tomato epigenetics: Deciphering the beyond genetic information in a vegetable fleshy-fruited crop
(2019-05-28)
The first natural plant mutant for which the molecular basis was determined to be an epimutation rather than a change in DNA sequence was a peloric variant of toadflax, Linaria vulgaris. Remarkably, the second example of ...
Epigenetics and autoimmune diseases
(Universidad del Rosario, 2012)
Epigenetics is defined as the study of all inheritable and potentially reversible changes in genome function that do not alter the nucleotide sequence within the DNA. Epigenetic mechanisms such as DNA methylation, histone ...
Exploring the Stress Impact in the Paternal Germ Cells Epigenome: Can Catecholamines Induce Epigenetic Reprogramming?
(Frontiers Media, 2021-02)
Spermatogenesis is characterized by unique epigenetic programs that enable chromatin remodeling and transcriptional regulation for proper meiotic divisions and germ cells maturation. Paternal lifestyle stressors such as ...
Epigenetic mechanisms related to cognitive decline during aging
(Veterinary and Human Toxicology, 2019-05)
Cognitive decline is a hallmark of the aging nervous system, characterized by increasing memory loss and a deterioration of mental capacity, which in turn creates a favorable context for the development of neurodegenerative ...
RG108 increases NANOG and OCT4 in bone marrow-derived mesenchymal cells through global changes in DNA modifications and epigenetic activation
(Public Library Science, 2018-12-03)
Human bone marrow-derived mesenchymal stem cells (hBMSCs) are important for tissue regeneration but their epigenetic regulation is not well understood. Here we investigate the ability of a non-nucleoside DNA methylation ...
Toward incorporating epigenetics into regulation of gene expression in the parasite Trichomonas vaginalis
(Wiley Blackwell Publishing, Inc, 2021-02)
Trichomonas vaginalis is an extracellular parasite that colonizes the human urogenital tract, causing a highly prevalent sexually transmitted infection. The parasite must change its transcriptional profile in order to ...
A comprehensive study of epigenetic alterations in hepatocellular carcinoma identifies potential therapeutic targets
(Elsevier Science, 2019-03)
Background & Aims: A causal link has recently been established between epigenetic alterations and hepatocarcinogenesis, indicating that epigenetic inhibition may have therapeutic potential. We aimed to identify and target ...
Infections And Epigenetic Changes In Cancer
(2016)
The role of epigenetics and infectious diseases at early stages of life influence premalignant lesions of cancer, in particular, gastric cancer, one of the most frequent tumours in Chile, Latin America, and worldwide. This ...
Infections and epigenetic changes in cancer
(2016)
The role of epigenetics and infectious diseases at early stages of life influence pre-malignant lesions of cancer, in particular, gastric cancer, one of the most frequent tumours in Chile, Latin America, and worldwide. ...