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Short-term effects of endothelins on tyrosine hydroxylase activity and expression in the olfactory bulb of normotensive rats
(Springer/Plenum Publishers, 2009-05)
The olfactory system in rats is part of the limbic region with extensive afferent connections with brain areas involved in the regulation of behaviour and autonomic responses. The existence of the endothelin system and ...
Central endothelin ETB receptor activation reduces blood pressure and catecholaminergic activity in the olfactory bulb of deoxycorticosterone acetate-salt hypertensive rats
(Elsevier Science Inc, 2020-10)
Endothelins regulate catecholaminergic activity in the olfactory bulb (OB) in normotensive and hypertensive animals. Administration of an endothelin ETA receptor antagonist decreases blood pressure in deoxycorticosterone ...
Plasmatic biochemical variables associated with polymorphisms in the endothelin-1 and endothelin-1 receptor a genes in hypertensive patients : pilot study
(2016)
Aims: Endothelin-1 (ET-1) is a potent vasoconstrictive peptide, and its activity is mediated by the type A receptor (EDNRA). This action may play a significant role in the etiology of hypertension. There are different works ...
EFFECTS of ENDOTHELIN-1 ON the ISOLATED GUINEA-PIG ILEUM - ROLE of NA+ IONS
(Springer, 1990-12-01)
Endothelin-1 induced an unusual transient biphasic effect (relaxation followed by contraction) in the isolated guinea-pig ileum. the contractile component of the response was concentration-dependent in the dose range ...
The role of endothelin pathway in modulation of airway reactivity to methacholine in C57Bl/6 and BALB/c mice
(ELSEVIER SCIENCE BV, 2008)
Endothelin peptides have been shown to increase cholinergic neurotransmission in the airway. Genetic differences in airway responsiveness to methacholine where reported in mice. The present study compared the airway ...
Targeting endothelin ET(A) and ET(B) receptors inhibits antigen-induced neutrophil migration and mechanical hypernociception in mice
(SPRINGER, 2009)
Endothelin may contribute to the development of inflammatory events such as leukocyte recruitment and nociception. Herein, we investigated whether endothelin-mediated mechanical hypernociception (decreased nociceptive ...