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Involvement of brain-derived neurotrophic factor and neurogenesis in oestradiol neuroprotection of the hippocampus of hypertensive rats
(Wiley, 2010-09-15)
The hippocampus of spontaneously hypertensive rats (SHR) and deoxycorticosterone (DOCA)-salt hypertensive rats shows decreased cell proliferation and astrogliosis as well as a reduced number of hilar cells. These defects ...
Stress by noise produces differential effects on the proliferation rate of radial astrocytes and survival of neuroblasts in the adult subgranular zone
(2011)
The subgranular zone (SGZ) in the dentate gyrus contains radial astrocytes, known as Type-1 or Type-B cells, which generate neuroblasts (Type-2 cells or Type-D cells) that give rise to granular neurons. Stress increases ...
Células granulares do giro denteado recém-geradas em ratos epilépticos jovens e idosos apresentam dendritos basais
(Universidade Estadual Paulista (Unesp), 2009)
As células granulares do giro denteado do hipocampo são continuamente geradas na zona subgranular em mamíferos. Condições como epilepsia e envelhecimento podem alterar a proliferação celular e também certas características ...
Neuroprotection and sex steroid hormones: evidence of estradiol mediated protection in hypertensive encephalopathy
(Bentham Science Publishers, 2012)
Besides their effects on reproduction, estrogens exert neuroprotective effects for brain diseases. Thus, estrogens ameliorate the negative aspects of aging and age-associated diseases in the nervous system, including ...
Imipramine enhances cell proliferation and decreases neurodegeneration in the hippocampus after transient global cerebral ischemia in rats
(ELSEVIER IRELAND LTD, 2010)
This study was aimed to determine whether imipramine chronic treatment promotes neurogenesis in the dentate gyrus (DG) and interferes with neuronal death in the CA1 subfield of the hippocampus after transient global cerebral ...
Chronic unpredictable mild stress alters an anxiety-related defensive response, Fos immunoreactivity and hippocampal adult neurogenesis
(Amsterdam, 2013-08-01)
Previous results show that elevated T-maze (ETM) avoidance responses are facilitated by acute restraint. Escape, on the other hand, was unaltered. To examine if the magnitude of the stressor is an important factor influencing ...
Existence of a potential neurogenic system in the adult human brain
(2014-03-22)
Abstract
Background
Prevailingly, adult mammalian neurogenesis is thought to occur in discrete, separate locations known as neurogenic niches that are ...
Existence of a potential neurogenic system in the adult human brain
(2014-03-22)
Abstract
Background
Prevailingly, adult mammalian neurogenesis is thought to occur in discrete, separate locations known as neurogenic niches that are best characterized in ...
Hippocampal neurovascular and hypothalamic-pituitary-adrenal axis alterations in spontaneously type 2 diabetic GK rats
(Elsevier Science Inc, 2010-03)
Metabolic and vascular consequences of diabetes mellitus induce several CNS complications. The dentate gyrus of the hippocampus, a well-recognized target for diabetic alterations, is a neurogenic area associated with memory ...