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Both the dorsal hippocampus and the dorsolateral striatum are needed for rat navigation in the Morris water maze
(ELSEVIER SCIENCE BVAMSTERDAM, 2012)
The multiple memory systems theory proposes that the hippocampus and the dorsolateral striatum are the core structures of the spatial/relational and stimulus-response (S-R) memory systems, respectively. This theory is ...
Association between the expression of amphetamine-induced behavioral sensitization and Cdk5/p35 activity in dorsal striatum
(American Psychological Association, 2016-02)
Sensitization to psychostimulants is strongly influenced by the environmental context in which the drug is administered and little is known about the molecular mechanisms that regulate this process. Chronic treatment with ...
Regional heterogeneity of D2-receptor signaling in the dorsal striatum and nucleus accumbens
(Elsevier (Cell Press), 2018)
Abstract: Dopamine input to the dorsal and ventral striatum originates from separate populations of midbrain neurons. Despite differences in afferent inputs and behavioral output, little is known about how dopamine release ...
A Mechanism Linking Two Known Vulnerability Factors for Alcohol Abuse: Heightened Alcohol Stimulation and Low Striatal Dopamine D2 Receptors
(Elsevier, 2019-10-29)
Alcohol produces both stimulant and sedative effects in humans and rodents. In humans, alcohol abuse disorder is associated with a higher stimulant and lower sedative responses to alcohol. Here, we show that this association ...
The indirect amygdala-dorsal striatum pathway mediates conditioned freezing: Insights on emotional memory networks
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
The dorsal striatum (DS) is involved in various forms of learning and memory such as procedural learning, habit learning, reward-association and emotional learning. We have previously reported that bilateral DS lesions ...
Cross-tolerance between nitric oxide synthase inhibition and atypical antipsychotics modify nicotinamide-adenine-dinucleotide phosphate-diaphorase activity in mouse lateral striatum
(USA, 2019-02-05)
Previous research indicates that the subchronic administration of NG-nitro-L-arginine (L-NOARG) produces tolerance to haloperidol-induced catalepsy in Swiss mice. The present study aimed to further investigate whether ...
Tolerance to the cataleptic effect that follows repeated nitric oxide synthase inhibition may be related to functional enzymatic recovery
(SAGE PUBLICATIONS LTD, 2010)
Systemic or intra-striatal acute administration of nitric oxide synthase (NOS) inhibitors causes catalepsy in rodents. This effect disappears after sub-chronic treatment. The aim of the present study was to investigate if ...
Drugs of abuse inhibit striatal dopamine transmission evoked by prefrontal cortex inputs
(Elsevier, 2019)
Drugs of abuse target the reward system and have one common action in the brain: increasing dopamine (DA) in the striatum. Recently, it was shown that the activation of prefrontal cortex (PFC) inputs can evoke DA transients ...
Shape alterations in the striatum in chorea-acanthocytosis
(ELSEVIER IRELAND LTD, 2011)
Chorea-acanthocytosis (ChAc) is an uncommon autosomal recessive disorder due to mutations of the VPS13A gene, which encodes for the membrane protein chorein. ChAc presents with progressive limb and orobuccal chorea, but ...
Cross-tolerance between nitric oxide synthase inhibition and atypical antipsychotics modify nicotinamide-adenine-dinucleotide phosphate-diaphorase activity in mouse lateral striatum
(2019-01)
Previous research indicates that the subchronic administration of NG-nitro-L-arginine (L-NOARG) produces
tolerance to haloperidol-induced catalepsy in Swiss mice.
The present study aimed to further investigate whether ...