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Dipeptidyl peptidase IV inhibitor improves the salivary gland histology of spontaneously diabetic mice
(2013-07-01)
Objectives: The incretin-based therapy might be effective in patients possessing certain levels of preserved pancreatic beta-cells. However, doubts still exist regarding the efficacy of this atment in the recovery of tissues ...
Dipeptidyl peptidase IV inhibitor improves the salivary gland histology of spontaneously diabetic mice
(2013-07-01)
Objectives: The incretin-based therapy might be effective in patients possessing certain levels of preserved pancreatic beta-cells. However, doubts still exist regarding the efficacy of this atment in the recovery of tissues ...
Comparison of plasma dipeptidyl peptidase IV activity in two caiman species: Caiman latirostris and Caiman yacare (Crocodylia, Alligatoridae)
(Brill Academic Publishers, 2011-03)
Dipeptidyl peptidase IV (DPPIV) is a well-characterized protease with broad substrate specificity, functionally-related to the activity of many bioactive peptides. It plays an important role as physiological regulator of ...
Modulation of Diabetes by Natural Products and Medicinal Plants via Incretins
(Georg Thieme Verlag Kg, 2019-04)
Incretins are metabolic hormones released after a meal that increase insulin secretion from pancreatic β-cells. The two main incretins are the intestinal peptides glucagon-like peptide-1 and glucose-dependent insulinotropic ...
Bioactive Phaseolus lunatus peptides release from maltodextrin/gum arabic microcapsules obtained by spray drying after simulated gastrointestinal digestion
(Wiley Blackwell Publishing, Inc, 2019-06)
Bioactive peptides can be protected from the gastrointestinal environment by microencapsulation. The aim was to assess the effect of simulated gastrointestinal digestion on bioactive properties of P. lunatus peptides (ACE-I, ...
Dipeptidyl peptidase IV inhibition upregulates GLUT4 translocation and expression in heart and skeletal muscle of spontaneously hypertensive rats
(Elsevier B.V., 2013-01-05)
The purpose of the current study was to test the hypothesis that the dipeptidyl peptidase IV (DPPIV) inhibitor sitagliptin, which exerts anti-hyperglycemic and anti-hypertensive effects, upregulates GLUT4 translocation, ...
Dipeptidyl peptidase-4 inhibitors and risk of heart failure in type 2 diabetes: systematic review and meta-analysis of randomised and observational studies
(BMJ Publishing Group, 2016)
OBJECTIVES: To examine the association between dipeptidyl peptidase-4 (DPP-4) inhibitors and the risk of heart failure or hospital admission for heart failure in patients with type 2 diabetes. DESIGN: Systematic review ...
Avaliação da inibição da prolil oligopeptidase, dipeptidil peptidase e acetilcolinesterase por constituintes de plantas nativas do bioma Pampa- RS. Parâmetros bioquímicos e comportamentais de Phyllanthus tenellus.
(Universidade Federal de Santa MariaBrasilFarmacologiaUFSMPrograma de Pós-Graduação em FarmacologiaCentro de Ciências da Saúde, 2016-05-19)
In this work six native species of Biome Pampa- RS were selected: Spermacoce poaya, Borreria verticillata, Galianthe fastigiata (Rubiaceae), two species of Hypericum: Hypericum brasiliense e H.connatum e Phyllanthus tenellus ...