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Distinctive roles of PLD signaling elicited by oxidative stress in synaptic endings from adult and aged rats
(Elsevier Science, 2012-12)
The role of iron in oxidative injury in the nervous system has been extensively described. However, little is known about the role of lipid signal transduction in neurodegeneration processes triggered by iron overload. The ...
Phosphatidic acid and diacylglycerol generation is regulated by insulin in cerebral cortex synaptosomes from adult and aged rats
(Veterinary and Human Toxicology, 2005-07)
Insulin receptor associated with the cerebral cortex (CC) has been shown to be involved in brain cognitive functions. Furthermore, deterioration of insulin signaling has been associated with age-related brain degenera tion. ...
A novel light-dependent activation of DAGK and PKC in bovine photoreceptor nuclei
(Academic Press Ltd-elsevier Science Ltd, 2014-06)
In this work, we describe a selective light-dependent distribution of the lipid kinase 1,2-diacylglycerol kinase (EC 2.7.1.107, DAGK) and the phosphorylated protein kinase C alpha (pPKCalpha) in a nuclear fraction of ...
Deconstructing the DGAT1 enzyme: Binding sites and substrate interactions
(Elsevier B.V., 2015)
Comparative phytohormone pro les, lipid kinase and lipid phosphatase activities in barley aleurone, coleoptile, and root tissues
(Elsevier France-editions Scientifiques Medicales Elsevier, 2012-06-23)
We analyzed lipid kinase and lipid phosphatase activities and determined endogenous phytohormone levels by liquid chromatography–tandem mass spectrometry in root and coleoptile tissues following germination of barley ...
Insulin promotes diacylglycerol kinase activation by different mechanisms in rat cerebral cortex synaptosomes
(Wiley-liss, Div John Wiley & Sons Inc, 2006)
Insulin Action on Polyunsaturated Phosphatidic Acid Formation in Rat Brain: An “In Vitro” Model with Synaptic Endings from Cerebral Cortex and Hippocampus
(Springer/Plenum Publishers, 2009-12)
The highly efficient formation of phosphatidic acid from exogenous 1-stearoyl-2-arachidonoyl-sn-glycerol (SAG) in rat brain synaptic nerve endings (synaptosomes) from cerebral cortex and hippocampus is reported. Phosphatidic ...
Light-Induced Opening of the TRP Channel in Isolated Membrane Patches Excised from Photosensitive Microvilli from Drosophila Photoreceptors
(Elsevier, 2019)
Drosophila phototransduction occurs in light-sensitive microvilli arranged in a longitudinal structure of the photoreceptor, termed the rhabdomere. Rhodopsin (Rh), isomerized by light, couples to G-protein, which activates ...
Insulin-related signaling pathways elicited by light in photoreceptor nuclei from bovine retina
(Elsevier, 2015-11)
Retina light stimulation triggers phototransduction events as well as different signaling mechanisms in outer segments (sensorial portion) of photoreceptor cells. We have recently reported a novel lightdependent activation ...