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In situ evaluation of anticancer drug methotrexate-DNA interaction using a DNA-electrochemical biosensor and AFM characterization
(Royal Soc Chemistry, 2011-01-01)
An in situ evaluation of the dsDNA-methotrexate (MTX) interaction was performed by voltammetry using a DNA-electrochemical biosensor and characterized by atomic force microscopy (AFM) at a highly oriented pyrolytic graphite ...
In situ evaluation of anticancer drug methotrexate-DNA interaction using a DNA-electrochemical biosensor and AFM characterization
(Royal Soc Chemistry, 2011-01-01)
An in situ evaluation of the dsDNA-methotrexate (MTX) interaction was performed by voltammetry using a DNA-electrochemical biosensor and characterized by atomic force microscopy (AFM) at a highly oriented pyrolytic graphite ...
Disposable biosensors for clinical diagnosis
(American Scientific Publishers - ASPValencia, 2014-01)
We present an overview on the use of disposable electrochemical biosensors for diagnostics, focusing on the applications of these devices as immunosensors and DNA sensors in the point-of-care diagnostics. Analytical ...
Mimicking enzymatic effects of cytochrome P450 by an efficient biosensor for in vitro detection of DNA damage
(Elsevier, 2015-05)
A novel biosensor for detecting DNA damage induced by benzo(a)pyrene (BP) and its metabolite was presented 18 in this work. The nafion-solubilized single wall carbon nanotubes-ionic liquid (SWCNTs-NA-IL) composite film ...
Fabrication of a novel impedimetric biosensor for label free detection of DNA damage induced by doxorubicin
(Elsevier Science, 2019-02)
In this work, a novel impedimetric biosensor has been fabricated for detection of DNA damage induced by doxorubicin (DX). Cytochrome P450 reductase (CPR) is required for electron transfer from nicotinamide adenine dinucleotide ...
Label-free oligonucleotide-based SPR biosensor for the detection of the gene mutation causing prothrombin-related thrombophilia
(MDPI, 2020)
Prothrombin-related thrombophilia is a genetic disorder produced by a substitution of a single DNA base pair, replacing guanine with adenine, and is detected mainly by polymerase chain reaction (PCR). A suitable alternative ...
Indicator-free electrochemical DNA hybridization biosensor
(Elsevier B.V., 2014)
Polyaniline-based field effect transistor for DNA/RNA biomarker sensing: Comparison to electrochemical impedance and inorganic layer
(Elsevier B.V., 2021-02-01)
One relevant aspect of the research in materials science focus on studying materials properties for applications in the field of sensing and biosensing devices aiming to obtain portable, stable, sensitive, and low-cost ...
Biotin self-assembled monolayer for impedimetric genosensor for direct detection of HIV-1
(2020-03-01)
This study was performed to prove the feasibility of a direct impedimetric DNA genosensor by using biotin self-assembled monolayer (SAM). The sensor was composed of a gold rod with a SAM of biotin-modified 19-base ...