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Improvement of the antihypertensive capacity of candesartan and trityl candesartan by their SOD mimetic copper(II) complexes
(Elsevier Science Inc, 2013-08)
Two new complexes [Cu(Cand)(H2O)4] [1] and [Cu2(TCand)4(H2O)2]·4H2O [2] (Cand = candesartan; TCand = trityl candesartan) have been synthesized and thoroughly characterized. The FTIR, Raman, EPR and diffuse reflectance ...
Oxidative stress in hypertensive patients induces an increased contractility in vein grafts independent of endothelial function
(Hindawi Publishing Corporation, 2011-08)
Objective. To evaluate the impact of oxidative stress on vascular reactivity to vasoconstrictors and on nitric oxide (NO) bioavailability in saphenous vein (SV) graft with endothelial dysfunction from hypertensive patients ...
Human predecidual stromal cells have distinctive characteristics of pericytes : Cell contractility, chemotactic activity, and expression of pericyte markers and angiogenic factors
(2018-01)
Introduction
Human decidual stromal cells (DSCs) play a key role in maternal–fetal interactions. Precursors of DSCs (preDSCs) localize around vessels in both the endometrium and decidua. Previous studies suggested a ...
Cardiac contractility structure-activity relationship and ligand-receptor interactions; the discovery of unique and novel molecular switches in myosuppressin signaling
(Public Library of Science, 2015-03)
Peptidergic signaling regulates cardiac contractility; thus, identifying molecular switches, ligand-receptor contacts, and antagonists aids in exploring the underlying mechanisms to influence health. Myosuppressin (MS), a ...
Cardiac contractility of the African sharptooth catfish, Clarias gariepinus: role of extracellular Ca2+, sarcoplasmic reticulum, and β-adrenergic stimulation
(2021-01-01)
This study investigated the dependence of contraction from extracellular Ca2+, the presence of a functional sarcoplasmic reticulum (SR), and the effects of β-adrenergic stimulation using isometric cardiac muscle preparations. ...
Renal and vascular effects of Crotalus durissus cumanensis venom and its crotoxin fraction
(Universidade Estadual Paulista (Unesp), Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP), 2011-01-01)
In this study, we evaluated the actions of Crotalus durissus cumanensis venom (CDCmV), and its crotoxin (Crtx) fraction, on renal and vascular functions in Wistar rats. In isolated perfused kidneys, CDCmV (10 mu g/mL) ...
Cell therapy prevents structural, functional and molecular remodeling of remote non-infarcted myocardium
(Elsevier/North-Holland Biomedical PressAmsterdam, 2013-08-09)
Background/objectives: Therapy using bone marrow (BM) cells has been tested experimentally and clinically due to the potential ability to restore cardiac function by regenerating lost myocytes or increasing the survival ...
Cell therapy prevents structural, functional and molecular remodeling of remote non-infarcted myocardium
(Elsevier B.V., 2013-10-09)
Background/objectives: Therapy using bone marrow (BM) cells has been tested experimentally and clinically due to the potential ability to restore cardiac function by regenerating lost myocytes or increasing the survival ...