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Study of the in vitro metabolic profile of a new alpha(2)-adrenergic agonist Cheek for in rat and human liver microsomes by using liquid chromatography-multiple-stage mass spectrometry and nuclear magnetic resonance
(Elsevier B.V., 2019-08-05)
A potent synthetic alpha(2)-adrenergic agonist called PT-31, (3-(2-chloro-6-fluorobenzyI)-imidazolidine-2,4-dione), was recently detected as a potential drug to be used as an adjuvant drug to treat chronic pain. The excellent ...
Integrative Proteomic Analysis of Digestive Tract Glycosidases from the Invasive Golden Apple Snail, Pomacea canaliculata
(American Chemical Society, 2019-07-19)
The freshwater snail Pomacea canaliculata, an invasive species of global significance, possesses a well-developed digestive system and diverse feeding mechanisms enabling the intake of a wide variety of food. The identification ...
Mycotoxin co-occurrence in rice, oat flakes and wheat noodles used as staple foods in Ecuador
(2013)
The co-occurrence of aflatoxin B1 (AFB1), B2 (AFB2), G1 (AFG1) and G2 (AFG2), ochratoxin A (OTA), deoxynivalenol (DON), fumonisin B1 (FB1), zearalenone (ZEN), and HT-2 and T-2 toxins in the main Ecuadorian staple cereals ...
Rapid sample preparation procedure for As speciation in food samples by LC-ICP-MS
(TAYLOR & FRANCIS LTDABINGDON, 2012)
This paper describes a rapid method for arsenic (As) speciation by LC-ICP-MS in several types of food samples. Prior to analysis, samples were milled and the As species extracted from biological tissues by sonication in ...
Identification and Quantification, by HPLC-DAD-MS/MS, of Carotenoids and Phenolic Compounds from the Amazonian Fruit Caryocar villosum
(Amer Chemical SocWashingtonEUA, 2012)
A python-based pipeline for preprocessing lc–ms data for untargeted metabolomics workflows
(Molecular Diversity Preservation International, 2020-10)
Preprocessing data in a reproducible and robust way is one of the current challenges in untargeted metabolomics workflows. Data curation in liquid chromatography–mass spectrometry (LC–MS) involves the removal of biologically ...
Analysis of carvedilol enantiomers in human plasma using chiral stationary phase column and liquid chromatography with tandem mass spectrometry
(WILEY-BLACKWELLMALDEN, 2012)
Carvedilol is an antihypertensive drug available as a racemic mixture. (-)-(S)-carvedilol is responsible for the nonselective beta-blocker activity but both enantiomers present similar activity on a1-adrenergic receptor. ...
Exploring in vivo violacein biosynthesis by application of multivariate curve resolution on fused UV-VIS absorption, fluorescence, and liquid chromatography-mass spectrometry data
(Springer HeidelbergHeidelbergAlemanha, 2013)
In-depth two-year study of phenolic profile variability among olive oils from autochthonous and Mediterranean varieties in Morocco, as revealed by a LC-MS chemometric profiling approach
(Molecular Diversity Preservation International, 2016-12)
Olive oil phenolic fraction considerably contributes to the sensory quality and nutritional value of this foodstuff. Herein, the phenolic fraction of 203 olive oil samples extracted from fruits of 4 autochthonous Moroccan ...