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An immunohistochemical study of T and B lymphocyte density in prostatic hyperplasia and prostate carcinoma in dogs
(2019-02-01)
The aim of this study was to characterise T and B lymphocyte density in 6 normal prostates, 15 benign prostatic hyperplasia (BPH) and 24 prostate carcinomas (PCs) in dogs by immunohistochemistry. Results revealed a ...
Senescent CD4+CD28− T lymphocytes as a potential driver of Th17/Treg imbalance and alveolar bone resorption during periodontitis
(MDPI, 2022)
Senescent cells express a senescence-associated secretory phenotype (SASP) with a pro-inflammatory bias, which contributes to the chronicity of inflammation. During chronic inflammatory diseases, infiltrating CD4(+) T ...
Moderate exercise increases the metabolism and immune function of lymphocytes in rats
(SpringerNew YorkEUA, 2013)
DNA vaccine containing the mycobacterial hsp65 gene prevented insulitis in MLD-STZ diabetes
(2009-09-15)
Background: Our group previously demonstrated that a DNA plasmid encoding the mycobacterial 65-kDa heat shock protein (DNA-HSP65) displayed prophylactic and therapeutic effect in a mice model for tuberculosis. This protection ...
DNA vaccine containing the mycobacterial hsp65 gene prevented insulitis in MLD-STZ diabetes
(2009-09-15)
Background: Our group previously demonstrated that a DNA plasmid encoding the mycobacterial 65-kDa heat shock protein (DNA-HSP65) displayed prophylactic and therapeutic effect in a mice model for tuberculosis. This protection ...
Distribution of naive and memory/effector CD4+ T lymphocytes and expression of CD38 on CD8+ T lymphocytes in AIDS patients with tuberculosis
(Brazilian Society of Infectious Diseases, 2003-04-01)
CD4+ and CD8+ T lymphocyte counts, naive and memory/effector CD4+ T subpopulations, and the expression of CD38 on CD8+ T lymphocytes were evaluated in four groups: AIDS patients with tuberculosis (HIV/TB, n=14), HIV-1 ...
Normalization of FoxP3+ regulatory T cells in response to effective antiretroviral therapy
(Oxford University Press, 2011)
Regulatory T cells (Tregs) blunt uncontrolled immune responses. In advanced human immunodeficiency virus (HIV) infection, the total number of Tregs is decreased, but the proportion of T cells with a regulatory phenotype ...