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Simvastatin modulates β-catenin/MDR1 expression on spheres derived from CF41.Mg canine mammary carcinoma cells
(Polish Academy of Sciences, 2018)
© 2018 Polish Academy of Sciences. All rights reserved. The presence of cancer stem-like cells (CSC) within canine mammary tumors, may explain partly local recurrence and spreading, since their ability to resist conventional ...
Estrogen receptor beta (ER beta) mediates expression of beta-catenin and proliferation in prostate cancer cell line PC-3
(Elsevier Ireland Ltd, 2016)
The aim of the present study was to characterize the mechanism underlying estrogen effects on the androgen-independent prostate cancer cell line PC-3. 17 beta-estradiol and the ER beta-selective agonist DPN, but not the ...
In vitro studies revealed a downregulation of Wnt/β-catenin cascade by active vitamin D and TX 527 analog in a Kaposi's sarcoma cellular model
(Pergamon-Elsevier Science Ltd, 2020-03)
The Kaposi´s sarcoma-associated herpesvirus G-protein-coupled receptor (vGPCR) is a key molecule in the pathogenesis of Kaposi´s sarcoma. We have previously demonstrated that 1α,25(OH)2D3 or its less calcemic analogTX 527 ...
Increased nuclear beta-catenin expression in oral potentially malignant lesions: A marker of epithelial dysplasia
(Medicina Oral, 2015)
Background: Deregulation of beta-catenin is associated with malignant transformation; however, its relationship with potentially malignant and malignant oral processes is not fully understood. The aim of this study was to ...
Increased nuclear β-catenin expression in oral potentially malignant lesions: A marker of epithelial dysplasia
(Medicina Oral, Patologia Oral y Cirugia Bucal, 2015)
Background: Deregulation of β-catenin is associated with malignant transformation; however, its relationship with potentially malignant and malignant oral processes is not fully understood. The aim of this study was to ...
Expression profile of components of the beta-catenin destruction complex in oral dysplasia and oral cancer
(Medicina Oral, 2021)
Background: Oral cancer represents the sixth most common cancer in the world and is associated with 40-50%
survival at 5 years. Within oral malignancies, oral squamous cell carcinoma (OSCC) is commonly preceded by
potentially ...
Activation of β-catenin signaling in androgen receptor-negative prostate cancer cells
(American Association for Cancer Research, 2012-02)
Purpose: To study Wnt/β-catenin in castrate-resistant prostate cancer (CRPC) and understand its function independently of the β-catenin-androgen receptor (AR) interaction. Experimental Design: We carried out β-catenin ...