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Sonic hedgehog in cancer stem cells: A novel link with autophagy
(2012)
The Sonic Hegdehog/GLI (SHH/GLI) pathway has been extensively studied for its role in developmental and cancer biology. During early embryonic development the SHH pathway is involved mainly in pattern formation, while in ...
Determinants of anti-cancer effect of mitochondrial electron transport chain inhibitors: Bioenergetic profile and metabolic flexibility of cancer cells
(Bentham Science Publishers B.V., 2016)
© 2016 Bentham Science Publishers. Recent evidence highlights that energy requirements of cancer cells vary greatly from normal cells and they exhibit different metabolic phenotypes with variable participation of both ...
Differential expression of CD90 and CD14 stem cell markers in malignant breast cancer cell lines
(WILEY-BLACKWELLHOBOKEN, 2012)
The recently emerged concept of cancer stem cell (CSC) has led to a new hypothesis on the basis for tumor progression. Basically, the CSC theory hypothesizes the presence of a hierarchically organized and relatively rare ...
Curcumin and paclitaxel induce cell death in breast cancer cell lines
(2018)
Breast cancer is one of the major health issues confronting women; however, treatment with conventional chemotherapeutic drugs is limited. Currently, paclitaxel is used as a therapeutic clinical agent to treat breast cancer ...
Cancer stem cell impact on clinical oncology
(2018)
Cancer is a widespread worldwide chronic disease. In most cases, the high mortality rate from cancer corre- lates with a lack of clear symptoms, which results in late diagnosis for patients, and consequently, advanced tumor ...
An integrative model of cancer cell differentiation with immunotherapy
(IOP Publishing, 2021-10)
In order to improve cancer treatments, cancer cell differentiation and immunotherapy are the subjects of several studies in different branches of interdisciplinary sciences. In this work, we develop a new population model ...
Macrophage migration inhibitory factor and oral cancer
(2013-05-01)
Background: Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine with pro-inflammatory functions and involved in tumorigenesis. The aim of this study was to evaluate the expression and localization of the ...
Macrophage migration inhibitory factor and oral cancer
(2013-05-01)
Background: Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine with pro-inflammatory functions and involved in tumorigenesis. The aim of this study was to evaluate the expression and localization of the ...