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Mostrando ítems 11-20 de 107
Structural basis for dimer formation of the CRISPR-associated protein Csm2 of Thermotoga maritima
(Wiley-Blackwell, 2016)
The clusters of regularly interspaced short palindromic repeats (CRISPR) and the Cas (CRISPR-associated) proteins form an adaptive immune system in bacteria and archaea that evolved as an RNA-guided interference mechanism ...
Aplicabilidade clínica da técnica CRISPR-Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats) no tratamento da anemia falciforme: uma revisão integrativa
(Universidade Federal de São CarlosUFSCarCâmpus São CarlosBiotecnologia - Biotec-Ar, 2020-12-18)
Introduction and objective: Sickle cell disease is the most common hemoglobinopathy in humans and has a high morbidity and mortality rates. It is caused by a point mutation, an A-T substitution (GAG→GTG) in the first exon ...
Novel CRISPR-based detection of Leishmania species
(Frontiers Media, 2022)
Tegumentary leishmaniasis, a disease caused by protozoan parasites of the genus Leishmania, is a major public health problem in many regions of Latin America. Its diagnosis is difficult given other conditions resembling ...
Improvement of baculovirus as protein expression vector and as biopesticide by CRISPR/Cas9 editing
(John Wiley & Sons Inc, 2019-08)
The clustered regularly interspaced short palindromic repeats (CRISPR) system?associated Cas9 endonuclease is a molecular tool that enables specific sequence editing with high efficiency. In this study, we have explored ...
CRISP y el nacimiento en China de dos niñas editadas genéticamente: abriendo la caja de Pandora
(La LeyPE, 2018)
El autor comenta las implicancias para el Derecho y la Bioética del reciente nacimiento de dos niñas en China mediante la técnica de edición genética llamada CRISP, la cual permite no solo corregir sino también modificar ...
Genome editing in potato via CRISPR-Cas9 ribonucleoprotein delivery
(Wiley Blackwell Publishing, Inc, 2018-12)
Clustered regularly interspaced short palindromic repeats and CRISPR-associated protein-9 (CRISPR-Cas9) can be used as an efficient tool for genome editing in potato (Solanum tuberosum). From both a scientific and a ...
Genome Editing By Crispr/cas9: A Game Change In The Genetic Manipulation Of Protists
(Blackwell Publishing Inc., 2016)