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Limits to clinical trials in surgical areas
(Faculdade de Medicina / USP, 2011)
Randomized clinical trials are considered to be the gold standard of evidence-based medicine nowadays. However, it is important that we point out some limitations of randomized clinical trials relating to surgical ...
Twenty-two years’ experience registering trials in a low-middle income country: The Peruvian Clinical Trial Registry
(Blackwell Publishing Inc., 2019)
Aim: This study analyzes the quantitative and qualitative evolution of the Peruvian Clinical Trial Registry during the last 22 years. Methods: Following a cross-sectional design, we reviewed all clinical trials registered ...
Twenty-two years’ experience registering trials in a low-middle income country: The Peruvian Clinical Trial Registry
(Blackwell Publishing Inc., 2019)
Aim: This study analyzes the quantitative and qualitative evolution of the Peruvian Clinical Trial Registry during the last 22 years. Methods: Following a cross-sectional design, we reviewed all clinical trials registered ...
The Latin American ongoing clinical trial register (LATINREC)
(PAN AMER HEALTH ORGANIZATION, 2006)
An ounce of prevention and a pound of cure: Randomized clinical trials of therapeutics against COVID-19 and an assessment of personal protective equipment and distancing
Given the multitudinous clinical characteristics of SARSCoV-2 infection (the cause of the COVID-19 pandemic),
the medical profession’s early response to managing
afflicted patients effectively amounted to throwing ...
Brazilian Clinical Trials Registry and the challenges for clinical research governance
(Wiley-Blackwell, 2023)
Differences between the real and the desired worlds in the results of clinical trials
(2015-01-01)
OBJECTIVE: We refer to the effectiveness (known as pragmatic or real world) and efficacy (known as explanatory or desired or ideal world) of interventions. However, these terms seem to be randomly chosen by investigators ...
Motivation and frustration in cardiology trial participation: the patient perspective
(Faculdade de Medicina / USP, 2012)
OBJECTIVE: The participation of humans in clinical cardiology trials remains essential, but little is known regarding participant perceptions of such studies. We examined the factors that motivated participation in such ...
Motivation and frustration in cardiology trial participation: The patient perspective
(Universidade de São Paulo (USP), Hospital das Clínicas, 2012-01-01)
OBJECTIVE: The participation of humans in clinical cardiology trials remains essential, but little is known regarding participant perceptions of such studies. We examined the factors that motivated participation in such ...