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Mostrando ítems 11-20 de 137
Effect of the electrostatic potential on the internalization mechanism of cell penetrating peptides derived from tirap
(KOREAN SOC BIOTECHNOLOGY & BIOENGINEERING, 2012)
Oligoarginine peptide conjugated to BSA improves cell penetration of gold nanorods and nanoprisms for biomedical applications
(MDPI, 2021)
Gold nanoparticles (AuNPs) have been shown to be outstanding tools for drug delivery and biomedical applications, mainly owing to their colloidal stability, surface chemistry, and
photothermal properties. The biocompatibility ...
Crotamine toxicity and efficacy in mouse models of melanoma
(INFORMA HEALTHCARE, 2011)
Objectives: Selective anticancer cell activity for both cell-penetrating and cationic antimicrobial peptides has previously been reported. As crotamine possesses activities similar to both of these, this study investigates ...
TAT-mediated transduction of bacterial redox proteins generates a cytoprotective effect on neuronal cells
(Public Library of Science, 2017-09)
Cell penetrating peptides, also known as protein transduction domains, have the capacity to ubiquitously cross cellular membranes carrying many different cargos with negligible cytotoxicity. As a result, they have emerged ...
Enhanced skin penetration of P20 phosphopeptide using protein transduction domains
(ELSEVIER SCIENCE BV, 2008)
Protein transduction domains (PTDs) were recently demonstrated to increase the penetration of the model peptide P20 when the PTD and P20 were covalently attached. Here, we evaluated whether non-covalently linked PTDs were ...
Antimicrobial Peptide K0-W6-Hya1 Induces Stable Structurally Modified Lipid Domains in Anionic Membranes
(2018-02-06)
Considering the known different mode of action of antimicrobial peptides in zwitterionic and anionic cell membranes, the present work compares the action of the antimicrobial peptide K0-W6-Hya1 (KIFGAIWPLALGALKNLIK-NH2) ...
Inhibition of malaria parasite Plasmodium falciparum development by crotamine, a cell penetrating peptide from the snake venom
(Elsevier Science Inc, 2016)
We show here that crotamine, a polypeptide from the South American rattlesnake venom with cell penetrating and selective anti-fungal and anti-tumoral properties, presents a potent anti-plasmodial activity in culture. ...
Influencia de la composición lipídica de modelos de membrana en la incorporación de péptidos penetrantes de célulasInfluence of the lipid composition of membrane models on the incorporation of cell penetrating peptides
(2018)
Los péptidos penetrantes de células pueden ser utilizados en diversas aplicaciones terapéuticas. Éstos son ampliamente utilizados para promover el ingreso al interior de la célula de moléculas conjugadas. En la actualidad ...