Buscar
Mostrando ítems 11-20 de 44
Multiple sites of tumorigenesis in transgenic mice overproducing hCG
(Elsevier Ireland, 2005-02)
We have produced transgenic (TG) mice expressing under the ubiquitin C promoter either the glycoprotein hormone common alpha-subunit (C(alpha)) or human chorionic gonadotropin (hCG) beta-subunit. C(alpha) overexpression ...
Quantifying Nonnative Interactions in the Protein-Folding Free-Energy Landscape
(Cell Press, 2016-07-26)
Protein folding is a central problem in biological physics. Energetic roughness is an important aspect that controls protein-folding stability and kinetics. The roughness is associated with conflicting interactions in the ...
Unusual C,O-fused glycosylapigenins from serjania marginata leaves
(Amer Chemical Soc, 2015-01-01)
A phytochemical study of a Serjania marginata leaf extract with antiulcer activity afforded 15 compounds, including the new 3-O-alpha-L-arabinopyranosyl(1 -> 3)-alpha-L-rhamnopyranosyl(1 -> 2)[beta-D-glucopyranosyl(1 -> ...
Rapidly varying boundaries in equations with nonlinear boundary conditions. The case of a Lipschitz deformation
(World Scientific Publ Co Pte Ltd, 2007-10-01)
We analyze the behavior of solutions of nonlinear elliptic equations with nonlinear boundary conditions of type partial derivative u/partial derivative n + g( x, u) = 0 when the boundary of the domain varies very rapidly. ...
Rapidly varying boundaries in equations with nonlinear boundary conditions. The case of a Lipschitz deformation
(World Scientific Publ Co Pte Ltd, 2007-10-01)
We analyze the behavior of solutions of nonlinear elliptic equations with nonlinear boundary conditions of type partial derivative u/partial derivative n + g( x, u) = 0 when the boundary of the domain varies very rapidly. ...
Distinguishing Biomolecular Pathways and Metastable States
(Amer Chemical Soc, 2019-11-01)
Protein folding occurs in a high dimensional phase space, and the representation of the associated energy landscape is nontrivial. A widely applied approach to studying folding landscapes is to describe the dynamics along ...
Supersymmetric quantum mechanics method for the Fokker-Planck equation with applications to protein folding dynamics
(Elsevier B.V., 2018-03-01)
This work developed analytical methods to explore the kinetics of the time-dependent probability distributions over thermodynamic free energy profiles of protein folding and compared the results with simulation. The ...
Long-range correlations ((n)j (C,H) n > 3) in the HMBC spectra of 3-(4-oxo-4H-chromen-3-YL)-acrylic acid ethyl esters
(SOC BRASILEIRA QUIMICA, 2005-05)
A systematic study about the long-range correlations observed in the HMBC spectra of a series of cis and trans 3-(4-oxo-4H-chromen-3-yl)-acrylic acid ethyl esters, and 5-hydroxy derivatives, was carried out. The results ...
Sulfur-substituted α-alkyl phenethylamines as selective and reversible MAO-A inhibitors: Biological activities, CoMFA analysis, and active site modeling
(2005)
A series of phenethylamine derivatives with various ring substituents and with or without N-methyl and/or C-alpha methyl or ethyl groups was synthesized and assayed for their ability reversibly to inhibit monoamine oxidase ...