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Aeration step method for k(L)a measurement under growth conditions in pneumatic bioreactors
(Wiley-Blackwell, 2019-07-01)
Background Determination of the volumetric oxygen transfer coefficient (k(L)a) plays an important role in the design and characterization of bioreactors. Among all methods available, few techniques are suitable for the ...
Goal-directed Design of Dynamic Experiments for Cybernetic Models of Bioreactors
(Elsevier B.V., 2018-01)
The distinctive feature of cybernetic models of bioreactors is their capacity to account for regulatory mechanisms in a cell metabolism by modeling the synthesis of enzymes and their activities. From a process engineering ...
Sistema automático de supervisão e controle de cultivos de alta densidade celular de E. coli recombinante
(Universidade Federal de São CarlosBRUFSCarPrograma de Pós-Graduação em Engenharia Química - PPGEQ, 2011-12-22)
High cell density cultivations of recombinant E. coli are a fast and economical way to produce recombinant proteins. Through this bioprocess, products with high added value and pharmaceuticals of great importance such as ...
Two-phase and two-dimensional model describing heat and water transfer during solid-state fermentation within a packed-bed bioreactor
(2016-03-01)
In the current paper, a two-phase and two-dimensional model describing heat and water transfer in a packed-bed bioreactor (PBB) for solid-state fermentation (SSF) is proposed. The model considers most of the transport ...
DROSOPHILA S2 cell culture in a WAVE Bioreactor: potential for scaling up the production of the recombinant rabies virus glycoprotein
(Springer, 2018-06-01)
The transmembrane rabies virus glycoprotein (RVGP) is the main antigen of vaccine formulations used around the world to prevent rabies, the most lethal preventable infectious disease known. The objective of this work was ...
Biorreator wave como alternativa para expansão de células estromais mesenquimais
(Universidade Federal de São CarlosBRUFSCarPrograma de Pós-Graduação em Engenharia Química - PPGEQ, 2015-03-05)
Mesenchymal stromal cells (MSCs) are required by the scientific community in the development and enhancement of therapeutic techniques in different fields of medicine. The MSCs are present in small concentrations in tissues, ...
Fungal cellulases: Production by solid-state cultivation in packed-bed bioreactor using solid agro-industrial by-products as substrates and application for hydrolysis of sugarcane bagasseCelulases fúngicas: Produção por cultivo sólido em biorreator de leito empacotado usando resíduos sólidos agroindustriais como substratos e aplicação na hidrólise de bagaço de cana
(2020-01-01)
Cellulases are essential for the hydrolysis of lignocellulosic materials in the production of second generation ethanol. Solid-state cultivation is a process that provides high concentrations of enzymes that can be used ...
Realistic model of a solid substrate fermentation packed-bed pilot bioreactor
(Elsevier Ltd., 2008)
Avaliação de transferência de calor e massa em biorreator Airlift de bancada para a produção de ácido clavulânico.
(Universidade Federal de São CarlosBRUFSCarPrograma de Pós-Graduação em Engenharia Química - PPGEQ, 2005-03-28)
The importance of the airlift bioreactor has grown in the biotechnology
field by aspects as high oxygen transfer, with power input low.
In this work were study the conditions heat and mass transfer, as well
as the condenser ...
An unconventional two-stage cultivation strategy to increase the lipid content and enhance the fatty acid profile on Chlorella minutissima biomass cultivated in a novel internal light integrated photobioreactor aiming at biodiesel production
(Elsevier B.V., 2020-08-01)
Biodiesel quality is dependent upon the fatty acids distribution of the raw material used in the trans/esterification reactions. While microalgae cells are regarded as potential oil suppliers for the biodiesel production ...