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Fridericia platyphylla (Cham.) L.G. Lohmann root extract exerts cytotoxic and antiproliferative effects on gastric tumor cells and downregulates BCL-XL, BIRC5, and MET genes
(2020-03-01)
Fridericia platyphylla (Cham.) L.G. Lohmann (FP) has cytotoxic, anti-inflammatory, and analgesic properties. We aimed to characterize the cytotoxic and antiproliferative effects of FP extract on normal (GAS) and tumor-derived ...
Survivin And Reprimo Expression Are Mutually Exclusive In Gastric Cancer
(2016)
Introduction: Gastric cancer, the leading cause of cancer-related deaths in Chile, is associated with changes in p53. The aim of this study was to analyze in silico and in vitro expression of p53 and associated apoptosis ...
Multidimensional integrative analysis uncovers driver candidates and biomarkers in penile carcinoma
(2017-12-01)
Molecular data generation and their combination in penile carcinomas (PeCa), a significant public health problem in poor and underdeveloped countries, remain virtually unexplored. An integrativemethodology combin ing ...
Papel del canal iónico TRPM4 en el desarrollo del cáncer de próstata en un modelo murino transgénico
(Universidad de Chile, 2013)
Estudios recientes demuestran aumentos significativos en la expresión del
canal TRPM4 (Transient Receptor Potential Melastatin 4) en cáncer de próstata
(CaP). En líneas celulares se ha descrito que TRPM4 aumenta la ...
The 5’ untranslated region of the anti-apoptotic protein Survivin contains an inhibitory upstream AUG codon
(Elsevier, 2020)
Survivin (BIRC5) is an anti-apoptotic protein that is important in cancer. Mechanisms responsible for controlling Survivin levels in cells include transcriptional regulation and modulation of protein stability via ...
Uso de microarray para determinação da expressão gênica diferencial em oócitos Bos Taurus Indicus e Bos Taurus Taurus submetidos ao estresse térmico
(Universidade Estadual Paulista (Unesp), 2014-03-27)
Genetic divergences in thermotolerance have been demonstrated between Bos taurus taurus (Holstein) and Bos taurus indicus (Nelore) animals. The deleterious effect of heat stress on oocyte developmental potential is greater ...
Evaluation of the effect of epigalocatequin galato on resistant phenotype to photodynamic therapy of an in vitro model of scamous cell cancer of the skin.Evaluación del efecto de epigalocatequin galato sobre el fenotipo resistente a terapia fotodinámica de un modelo in vitro de cáncer de células escamosas de piel.
(2019)
Non-melanoma skin cancer (NSCLC) is the most frequent neoplasm worldwide, each year there are 2-3 million new cases. Frequent lesions of NSCLC such as basal cell carcinoma and squamous cell carcinoma precursor lesions can ...
Fator de crescimento fibroblástico 18 (FGF18) regula o efeito da progesterona e do hormônio luteinizante no período próximo à ovulação em bovinos
(Universidade Federal de Santa MariaBrasilMedicina VeterináriaUFSMPrograma de Pós-Graduação em Medicina VeterináriaCentro de Ciências Rurais, 2022-03-15)
The ovulatory peak of luteinizing hormone (LH) initiates a cascade of events in pre-ovulatory
follicles culminating in the rupture of the follicular wall and release of a cumulus-oocyte
complex ready to fertilization. ...