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Calcium and zinc decrease intracellular iron by decreasing transport during iron repletion in an in vitro model
(2017)
Abstract . Purpose Iron is an essential micronutrient that participates in a number of vital reactions and its absorption may be altered by various nutritional factors such as other micronutrients. Our hypothesis is that ...
Transport of the organic cations gonyautoxin 2/3 epimers, a paralytic shellfish poison toxin, through the human and rat intestinal epitheliums
(2002)
The aim of this work is to study the mechanisms involved in gonyautoxins (GTXs) intestinal absorption. For this purpose, we studied the transport of GTX 2/3 epimers by intestinal epithelial cell lines (IEC-6 and Caco-2) ...
Estandarización de un modelo basado en monocapas de células caco-2 con aplicación en estudios de absorción de fármacos
(Revista Colombiana de Ciencias Químico Farmacéuticas, 2006)
La biodisponibilidad de los fármacos administrados oralmente depende de su absorción y de su metabolismo. Entre los factores que determinan la absorción de un compuesto se encuentran la permeabilidad y las características ...
Synthesis and characterization of 3,6-O,O’- dimyristoyl chitosan micelles for oral delivery of paclitaxel
(2017-04-01)
The aim of the present study was to investigate the potential application of 3,6-O,O’- dimyristoyl chitosan DMCh, an amphiphilic derivative of chitosan, for improving the oral bioavailability of paclitaxel (PTX), a water ...
Efeitos da suplementação de fitosterol na expressão do MIR-33A/B
(Universidade Federal de São Paulo (UNIFESP), 2021)
Background: Phytosterols (Ps) are bioactive compounds found in plant foods, not synthetized by our body that inhibit diet and endogenous cholesterol (Ch) absorption in the intestine. When regularly consumed, the higher the ...
Desenvolvimento e caracterização de nanopartículas com propriedades mucoadesivas baseadas em ácido hialurônico para liberação cólon específica de metotrexato
(Universidade Estadual Paulista (Unesp), 2017-09-29)
A nanotecnologia farmacêutica é uma relevante ferramenta tecnológica para o desenvolvimento de novos sistemas para a veiculação de fármacos, pois devido às suas dimensões reduzidas são capazes de circular por capilares que ...