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Subsite specificity (S3, S2, S1 ', S2 ' and S3 ') of oligopeptidase B from Trypanosoma cruzi and Trypanosoma brucei using fluorescent quenched peptides: comparative study and identification of specific carboxypeptidase activity
(Portland Press Ltd, 2003-08-01)
We characterized the extended substrate binding site of recombinant oligopeptidase B enzymes from Trypanosoma cruzi (Tc-OP) and Trypanosoma brucei (Tb-OP), evaluating the specificity of their S3, S2, S1', S2' and S3' ...
Caracterización molecular y funcional de la enzima arginiltransferasa 1 (ATE1) en el proceso de autofagia
(2022-07-01)
Resumen: La enzima arginil-ARNt transferasa (Ate1) cataliza la transferencia de arginina desde un ARN de transferencia a una proteína aceptora. Este proceso conocido como arginilación postraduccional está involucrado en ...
Antitumor potential of fibulin-5 in breast cancer cells depends on its RGD cell adhesion motif
(Cell Physiol Biochem Press GmbH & Co KG, 2019)
Studies on the activation of the pre-kininogenin-kininogenin (pre-kallikrein-kallikrein) system by sulfated polysaccharides and kaolin
(1979-12-01)
The activation of pre-kininogenin to kininogenin (pre-kallikrein to kallikrein) is one of the steps in the series of reactions of a complex system, linked also to fibrinolysis and coagulation, that leads to kinin release ...
Studies on the activation of the pre-kininogenin-kininogenin (pre-kallikrein-kallikrein) system by sulfated polysaccharides and kaolin
(1979-12-01)
The activation of pre-kininogenin to kininogenin (pre-kallikrein to kallikrein) is one of the steps in the series of reactions of a complex system, linked also to fibrinolysis and coagulation, that leads to kinin release ...
Isolation and characterization of a cysteine proteinase from Fasciola hepatica adult worms
(Elsevier, 1989)
Adult Fasciola hepatica worms contain multiple proteinases capable of degrading hemoglobin, immunoglobulins and collagen. Here we report the isolation and biochemical characterization of a cysteine proteinase from acidic ...
Design and use of highly specific substrates of neutrophil elastase and proteinase 3
(Amer Thoracic Soc, 2004-06-01)
We have exploited differences in the structures of S2' subsites of proteinase 3 (Pr3) and human neutrophil elastase (FINE) to prepare new fluorogenic substrates specific for each of these proteases. the positively charged ...
Sistemas de efluxo multidrogas em Escherichia coli e uso de inibidores como possíveis adjuvantes na terapia da mastite bovina
(Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2018)
NEW SUBSTRATES of PAPAIN, BASED ON the CONSERVED SEQUENCE of NATURAL INHIBITORS of the CYSTATIN FAMILY
(Elsevier B.V., 1994-01-01)
A series of peptide substrates with different fluorogenic leaving groups has been synthesized. the peptide moiety in these substrates mimics a highly conserved sequence (QVVAG) in the natural reversible inhibitors of ...