Buscar
Mostrando ítems 11-20 de 1634
Multifarious roles of mTOR signaling in cognitive aging and cerebrovascular dysfunction of Alzheimer's disease
(Blackwell Publishing Ltd, 2020)
Mild cognitive impairment and the onset of Alzheimer's disease in older adults Deterioro cognitivo leve y enfermedad de Alzheimer inicial en adultos mayores
(2001)
The early detection of dementia carries implications for clinical management of patients and their families, and it is of utmost concern if an effective pharmacological treatment is to be found. We report the final clinical ...
PSEN1 and PSEN2 Gene Expression in Alzheimer's Disease Brain: A New Approach
(Ios Press, 2014-01-01)
Presenilin 1 (PSEN1) and presenilin 2 (PSEN2) genes encode the major component of y-secretase, which is responsible for sequential proteolytic cleavages of amyloid precursor proteins and the subsequent formation of ...
Brain-derived neurotrophic factor in the control human brain, and in Alzheimer's disease and Parkinson's disease
(Pergamon-Elsevier Science Ltd, 2001-01)
Brain-derived neurotrophic factor (BDNF) is a small dimeric protein, structurally related to nerve growth factor, which is abundantly and widely expressed in the adult mammalian brain. BDNF has been found to promote survival ...
Caspase-Cleaved Tau Impairs Mitochondrial Dynamics in Alzheimer’s Disease
(Humana Press Inc., 2018)