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Monoclonal-antibodies specific for the free alpha-subunit of glycoprotein hormones and their use in the development of a sensitive immunofluorometric assay
(Assoc Bras Divulg Cientifica, 1995-06-01)
Glycoprotein hormone free alpha subunit has been used as a marker for some pituitary tumors and to study the reactivity of glycoprotein hormone-producing cells under different circumstances. We describe a highly sensitive ...
CK2 alpha/CK1 alpha chimeras are sensitive to regulation by the CK2 beta subunit
(Springer, 2008)
The effect of CK2 beta on the activity of CK2 alpha and other protein kinases that can bind this regulatory subunit is not fully understood. In an attempt to improve our understanding of this effect, chimeras of CK2 alpha ...
Regulation of PKD1-mediated Golgi to cell surface trafficking by Gαq subunits
(Wiley, 2013-12)
Background Information: Heterotrimeric GTP-binding proteins play a key role in cell trafficking regulation. Above all, specific Gβγ subunits have been shown to be a major component of a signal transduction pathway, which ...
The 20S proteasome alpha(5) subunit of Arabidopsis thaliana carries an RNase activity and interacts in planta with the Lettuce mosaic potyvirus HcPro protein
(Wiley-Blackwell, 2011-02-01)
P>In plants, the ubiquitin/26S proteasome system (UPS) plays a central role in protein degradation and is involved in many steps of defence mechanisms, regardless of the types of pathogen targeted. In addition to its ...
Activating GNAS1 gene mutations in patients with premature thelarche
(2004)
Objective To identify GNAS1 gene mutations in girls with exaggerated and/or chronic fluctuating thelarche for at least 1-year duration with no other signs of precocious puberty, skeletal dysplasia, or typical skin lesions ...
The association of Na,K-ATPase subunits studied by circular dichroism, surface tension and dilatational elasticity
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2008)
Different stoichiometries are observed between alpha and beta subunits of Na,K-ATPase that depend on the method employed to solubilize and purify the enzyme. It is not known whether this variability is due to loss of ...
Immunohistochemical localization of nicotinic acetylcholine-receptor subunits in the mesencephalon and diencephalon of the chick (Gallus-gallus)
(Wiley-Blackwell, 1992-03-22)
Monoclonal antibodies against two alpha-bungarotoxin-binding subunits (alpha-7 and alpha-8) of the nicotinic acetylcholine receptors (nAChRs) were used as immunohistochemical probes to map their distribution in the chick ...
Identification and Characterization of an Alternatively Spliced Isoform of the Human Protein Phosphatase 2A alpha Catalytic Subunit
(Amer Soc Biochemistry Molecular Biology IncBethesdaEUA, 2012)