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All you need is coffe
(Fundación Revista Medicina, 2017)
Cholinergic deficit is regarded as an important factor responsible for Alzheimer’s disease symptoms. Two molecular targets for the treatment of this disease are acetylcholinesterase (AChE) and nic otinic receptor (nAChR). ...
Molecular Docking and Molecular Dynamic Studies of Semi-Synthetic Piperidine Alkaloids as Acetylcholinesterase Inhibitors
(Soc Brasileira Quimica, 2012-01-01)
The mixture of semi-synthetic derivatives (-)-3-O-acetyl-cassine hydrochloride and (-)-3-O-acetyl-spectaline hydrochloride, prepared from the mixture of natural alkaloids (-)-cassine and (-)-spectaline (4:1) isolated from ...
Molecular Docking and Molecular Dynamic Studies of Semi-Synthetic Piperidine Alkaloids as Acetylcholinesterase Inhibitors
(Soc Brasileira Quimica, 2012-01-01)
The mixture of semi-synthetic derivatives (-)-3-O-acetyl-cassine hydrochloride and (-)-3-O-acetyl-spectaline hydrochloride, prepared from the mixture of natural alkaloids (-)-cassine and (-)-spectaline (4:1) isolated from ...
Activity of cytisine and its brominated isosteres on recombinant human a7, a4b2 and a4b4 nicotinic acetylcholine receptors
(International Society for Neurochemistry,, 2001-06-06)
Effects of cytisine (cy), 3-bromocytisine (3-Br-cy), 5-bromocytisine
(5-Br-cy) and 3,5-dibromocytisine (3,5-diBr-cy) on
human (h) a7-, a4b2- and a4b4 nicotinic acetylcholine (nACh)
receptors, expressed in Xenopus oocytes ...
Readthrough acetylcholinesterase (AChE-R) and regulated necrosis: pharmacological targets for the regulation of ovarian functions?
(Nature, 2015)
Proliferation, differentiation and death of ovarian cells ensure orderly functioning of the female gonad during the reproductive
phase, which ultimately ends with menopause in women. These processes are regulated by several ...
Readthrough acetylcholinesterase (AChE-R) and regulated necrosis: pharmacological targets for the regulation of ovarian functions?
(Nature, 2015)
Proliferation, differentiation and death of ovarian cells ensure orderly functioning of the female gonad during the reproductive
phase, which ultimately ends with menopause in women. These processes are regulated by several ...
(−)-Reboxetine inhibits muscle nicotinic acetylcholine receptors by interacting with luminal and non-luminal sites
(Elsevier, 2013-07)
The interaction of (−)-reboxetine, a non-tricyclic norepinephrine selective reuptake inhibitor, with muscle-type nicotinic acetylcholine receptors (AChRs) in different conformational states was studied by functional and ...
Molecular modeling of cardanol-derived AChE inhibitors
(Elsevier B.V., 2019)
Estudos bioquímicos e cinéticos de acetilcolinesterases de formigas cortadeiras (Atta sexdens)
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Química - PPGQCâmpus São Carlos, 2017-09-29)
Acetylcholinesterase (AChE) (EC 3.1.1.7) is the enzyme responsible for catalyzing the hydrolysis of the neurotransmitter acetylcholine leading to the release of acetate and choline. In insects, acetylcholine is one of the ...