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Self-assembly and anti-amyloid cytotoxicity activity of amyloid beta peptide derivatives
(Nature Publishing Group, 2017-03)
The self-assembly of two derivatives of KLVFF, a fragment Aβ(16-20) of the amyloid beta (Aβ) peptide, is investigated and recovery of viability of neuroblastoma cells exposed to Aβ (1-42) is observed at sub-stoichiometric ...
An intramolecular O-N migration reaction on gold surfaces: Toward the preparation of well-defined amyloid surfaces
(2009)
Amyloids are a family of self-aggregating proteins implicated in various central nervous system disorders, including Alzheimer's disease (AD). It is thought that prefibrillar soluble forms of amyloid peptides, including ...
Altered β-amyloid precursor protein isoforms in Mexican Alzheimer’s Disease patients
(IOS Press and the authors., 2015)
Metabolic abnormalities of erythrocytes as a risk factor for Alzheimer's disease
(Frontiers Media S.A., 2018)
Binding Modes of Phthalocyanines to Amyloid β Peptide and Their Effects on Amyloid Fibril Formation
(Cell Press, 2018-03)
The inherent tendency of proteins to convert from their native states into amyloid aggregates is associated with a range of human disorders, including Alzheimer's and Parkinson's diseases. In that sense, the use of small ...
Sub-lethal levels of amyloid β-peptide oligomers decrease non-transferrin-bound iron uptake and do not potentiate iron toxicity in primary hippocampal neurons
(2012)
Two major lesions are pathological hallmarks in Alzheimer's disease (AD): the presence of neurofibrillary tangles formed by intracellular aggregates of the hyperphosphorylated form of the cytoskeletal tau protein, and of ...
Release of Acetylcholinesterase (AChE) from β-Amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice
(2008)
The major protein constituent of amyloid deposits in Alzheimer's disease (AD) is the amyloid-beta-peptide (Abeta). Amyloid deposits contain "chaperone molecules" which play critical roles in amyloid formation and toxicity. ...
Release of Acetylcholinesterase (AChE) from β-Amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice
(2008)
The major protein constituent of amyloid deposits in Alzheimer's disease (AD) is the amyloid-beta-peptide (Abeta). Amyloid deposits contain "chaperone molecules" which play critical roles in amyloid formation and toxicity. ...