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Abnormally high digestive enzyme activity and gene expression explain the contemporary evolution of a diabrotica biotype able to feed on soybeans
(Wiley, 2012-06)
Western corn rootworm (Diabrotica virgifera) (WCR) depends on the continuous availability of corn. Broad adoption of annual crop rotation between corn (Zea mays) and nonhost soybean (Glycine max) exploited WCR biology to ...
Decreased level of antibodies and cardiac involvement in patients with chronic Chagas heart disease vaccinated with BCG
(Springer, 2014-04)
Studies indicate that Trypanosoma cruzi is capable of inducing immunological disturbances such as decreased expression of molecules involved in T-cell survival and costimulation for antigen-driven T-cell responses. On the ...
TAT-mediated transduction of bacterial redox proteins generates a cytoprotective effect on neuronal cells
(Public Library of Science, 2017-09)
Cell penetrating peptides, also known as protein transduction domains, have the capacity to ubiquitously cross cellular membranes carrying many different cargos with negligible cytotoxicity. As a result, they have emerged ...
How did a grass reach Antarctica? The Patagonian connection of Deschampsia antarctica (Poaceae)
(Oxford University Press, 2017-11)
Deschampsia antarctica is the only grass naturally occurring in Antarctica, and it is also indigenous to southern South America. We aimed to evaluate patterns of within-population genetic diversity and between the focal ...
Antitumor immunotherapeutic and toxic properties of an HDL-conjugated chimeric IL-15 fusion protein
(American Association for Cancer Research, 2013-01)
Interleukin (IL)-15 effects on CD8 T and natural killer (NK) lymphocytes hold promise to treat cancer. Fusion proteins have been engineered to provide IL-15 receptor alpha (IL-15Rα) mediated trans-presentation to lymphocytes ...
Changes in the Proliferation/Apoptosis Balance in the Bovine Ovary: A Key Early Event in Follicular Persistence
(Karger, 2017-11)
The objective of this work was to evaluate proliferation and apoptosis in the bovine ovary in a model of follicular persistence induced by low levels of progesterone to detect incipient changes during cystic ovarian disease ...
Reactive oxygen species and extracellular signal-regulated kinase 1/2 mediate hexachlorobenzene-induced cell death in FRTL-5 rat throyd cells
(Oxford University Press, 2013-05-24)
Hexachlorobenzene (HCB) is an organochlorine pesticide widely distributed in the environment. We have previously shown that chronic HCB exposure triggers apoptosis in rat thyroid follicular cells. This study was carried ...
Experimental hybridization and reproductive isolation between two sympatric species of tephritid fruit flies in the Anastrepha fraterculus species group
(Wiley Blackwell Publishing, Inc, 2017-06)
Among tephritid fruit flies, hybridzation has been found to produce local adaptationand speciation, and in the case of pest species, induce behavioral and ecological alterations that can adversely impact efficient pest ...
Solanesyl diphosphate synthase, an enzyme of ubiquinone synthetic pathway, is required throughout the life cycle of Trypanosoma brucei
(American Society For Microbiology, 2014-02)
Ubiquinone 9 (UQ9), the expected product of the long-chain solanesyl diphosphate synthase of Trypanosoma brucei (TbSPPS), has a central role in reoxidation of reducing equivalents in the mitochondrion of T. brucei. The ...
Chemical signatures of formation processes in the stellar populations of simulated galaxies
(Oxford University Press, 2012-02)
We study the chemical properties of the stellar populations in eight simulations of the formation of Milky Way mass galaxies in a cold dark matter universe. Our simulations include metaldependent cooling and an explicitly ...