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Mostrando ítems 151-160 de 213
Avaliação da toxicidade e correlação com polimorfismos no gene de reparo X-RCC1 em pacientes com neoplasias do trato gastrointestinal submetidos a radio e quimioterapia
(Universidade Federal do ParáBrasilNúcleo de Pesquisas em OncologiaUFPAPrograma de Pós-Graduação em Oncologia e Ciências Médicas, 2017)
Crispr/cas9-induced Disruption Of Paraflagellar Rod Protein 1 And 2 Genes In Trypanosoma Cruzi Reveals Their Role In Flagellar Attachment
(American Society for Microbiology, 2015)
Noninfectious complications in patients with pediatric-onset common variable immunodeficiency correlated with defects in somatic hypermutation but not in class-switch recombination
(Mosby-Elsevier, 2017-03)
Background Common variable immunodeficiency (CVID) is a heterogeneous syndrome characterized by impaired immunoglobulin production and usually presents with a normal quantity of peripheral B cells. Most attempts aiming to ...
XRCC2 R188H (rs3218536), XRCC3 T241M (rs861539) and R243H (rs77381814) single nucleotide polymorphisms in cervical cancer risk
(Springer, 2013-07)
Human Papillomavirus (HPV) is the main cause of cervical cancer and its precursor lesions. Transformation may be induced by several mechanisms, including oncogene activation and genome instability. Individual differences ...
Edição de genoma em Trypanosoma utilizando nucleases dedo de zinco e o sistema CRISPR/Cas9
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE BIOQUÍMICA E IMUNOLOGIAPrograma de Pós-Graduação em Bioquímica e ImunologiaUFMG, 2016-03-23)
Genetic manipulation in trypanosomatids is an essential tool to study these organisms, many of them are agents of important human and veterinary diseases. The introduction of exogenous DNA into the genome in any cell or ...
Use of proteomic analysis tools to identify HCV-proteins down-regulated by acetylsalicylic acid
(2013)
Background and aim. Acetylsalicylic acid (ASA) has been shown to downregulate HCV expression; however, the involved mechanisms are unknown. We used proteomic analysis to compare protein expression profiles between human ...