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Metformin action upon the endothelium diminishes the platelet-mediated increase in angiogenesis
(2016)
Introduction:More than 30% of ovarian cancer patients present increased platelet counts
(thrombocytosis) and has been associated with poor prognosis. Platelets have been reported to
increase angiogenesis through the release ...
Platelets induces angiogenesis and this effect is blocked by metformin in endothelial cells
(2015)
Introduction: Ovarian cancer is the leading cause of gynaecological cancer mortality worldwide. A complication of patients suffering from ovarian cancer is an increase in blood platelets (thrombocytosis), a situation ...
Combination of Melatonin and Metformin Hydrochloride for Treatment Polycystic Ovarian in Female Rats
(Universidade Federal do Rio Grande do Sul, 2016)