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Immunization of Balb/c mice with modified auto-antigens for induction of autoimmune sialoadenitis
(2007-12-01)
Sjögren's syndrome is an autoimmune disease characterized by sialoadenitis and elevated titers of autoantibodies. To assess whether it is possible to induce inflammatory changes in salivary gland tissues, a series of ...
Adaptação transcultural do EULAR Sjögren's Syndrome Disease Activity Index (ESSDAI) para a língua portuguesa
(Sociedade Brasileira de Reumatologia, 2013-12-01)
INTRODUCTION: The EULAR Sjögren's Syndrome Disease Activity Index (ESSDAI) is an index of primary Sjögren's syndrome (PSS) systemic activity. OBJECTIVE: To perform the ESSDAI transcultural adaptation into Brazilian Portuguese. ...
Sjögren's syndrome and the epithelial target : A comprehensive review
(2013-05)
The most difficult component in our understanding of human autoimmunity remains a rigorous dissection of etiological events. Indeed, the vast literature on autoimmune diseases focuses on the inflammatory response, with the ...
Mechanotransduction and epigenetic control in autoimmune diseases
(Elsevier, 2011)
Differentiation of epithelial cells is required to define tissue architecture and appropriate function of these
cells is associated with a specific pattern of gene expression. DNA methylation, post-translational
modification ...
Agregación de autoinmunidad en familias extremas con Síndrome de Sjogren: una aproximación a la medicina personalizada
(Universidad del RosarioFacultad de medicina, 2014)
Objective: to investigate aggregation of autoimmunity among first–degree relatives (FDR) of probands with Sjogren´s syndrome (SS) disclosing polyautoimmunity and familial autoimmunity.
Methods: this was a cross–sectional ...
Apoptosis and cell proliferation: the paradox of salivary glands in sjögren’s disease
(Sociedade Portuguesa de Reumatologia Vo. 33, pp. 299- 303, 2008)
Aim: To assess apoptosis and proliferation in salivary glands of patients with primary Sjögren’s syndrome.
Methods: Studies were performed in twenty four minor salivary glands from patients with primary
Sjögren’s syndrome ...
Primary Sjogren's syndrome presenting as a generalized Chorea
(ELSEVIER SCI LTD, 2005-05)
We report on a patient who presented with generalized chorea as the first manifestation of Sjogren Syndrome, and review the possible pathogenesis.
SAT0306 How does cigarette smoking affect Sjögren's syndrome?
Background Cigarette smoking has been found to play a pathogenic role in several autoimmune diseases. However, data about its influence on Sjögren's syndrome (SS) is scarce