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Mostrando ítems 121-130 de 747
Spatial distribution of Schistosoma mansoni infection before and after chemotherapy with two praziquantel doses in a community of Pernambuco, Brazil
(Instituto Oswaldo Cruz, Ministério da Saúde, 2012)
Glomerulopatia esquistossomótica: comportamentos das alterações em camundongos infectados pelo schistosoma mansoni, antes e depois do tratamento com praziquantel
(Centro de Pesquisas Gonçalo Moniz, 2013)
Elucidating the influence of praziquantel nanosuspensions on the in vivo metabolism of Taenia crassiceps cysticerci
(Elsevier Science, 2016-09)
The aim of this work was to develop nanosuspensions of praziquantel (PZQ) and to evaluate their influence on the energetic metabolism of cysticerci inoculated in BALB/c mice. We analyzed metabolic alterations of glycolytic ...
First steps in the formulation of praziquantel nanosuspensions for pharmaceutical applications
(Taylor & Francis, 2020-08)
Praziquantel (PZQ), a broad spectrum anthelmintic drug, cannot be found in acceptable dosage forms for elderly patients, paediatric patients, and for veterinary use. In fact, very little has been done up to now in the ...
Structural Elucidation of Poloxamer 237 and Poloxamer 237/Praziquantel Solid Dispersions: Impact of Poly(Vinylpyrrolidone) over Drug Recrystallization and Dissolution
(Springer, 2018-04)
Praziquantel (PZQ) is the recommended, effective, and safe treatment against all forms of schistosomiasis. Solid dispersions (SDs) in water-soluble polymers have been reported to increase solubility and bioavailability of ...
Praziquantel systems with improved dissolution rate obtained by high pressure homogenization
(Elsevier Science, 2018-12-01)
Praziquantel (PZQ), an antihelmintic agent commonly administered to humans and cattle, has low aqueous solubility, which compromises its bioavailability and efficacy. The purpose of this study was to develop a new formulation, ...
Estudo das interações do praziquantel com ciclodextrinas em sistemas multicomponentes
(BrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS FARMACÊUTICAS, 2016-11-28)
The use of cyclodextrin (CD) to enhace the praziquantel (PZQ) water solubility has been widely studied in the literature. In this present paper, the interaction has not yet studied between the PZQ and both the beta-cyclodextrin ...
Estudio comparativo de los tratamientos antihelmínticos de neurocisticercosis en ratas albinas Holtzman tratadas con albendazol-praziquantel y oxfendazol-praziquantel
(Universidad Nacional Mayor de San MarcosPE, 2018)
Se comparan los tratamientos antihelmínticos de albendazolpraziquantel y oxfendazol-praziquantel en ratas albinas holtzman infestadas experimentalmente como modelo de neurocisticercosis humana. Para ello, se administraron ...