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Estudo da disfunção mitocondrial em modelos de doença de Parkinson in vitro e in vivo e perspectivas terapêuticas
(Universidade Federal de Santa MariaBrasilBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica ToxicológicaCentro de Ciências Naturais e Exatas, 2021-10-01)
Parkinson disease (PD) is a neurodegenerative disease which symptoms are consequence of progressive neuron lost, especially dopaminergic neurons. Other feature related to PD is mitochondrial dysfunction which could target ...
The conundrum of UDP-Glc entrance into the yeast ER lumen
(Oxford University Press, 2016-12)
UDP-Glc entrance into the endoplasmic reticulum (ER) of eukaryotic cells is a key step in the quality control of glycoprotein folding, a mechanism requiring transfer of a Glc residue from the nucleotide sugar (NS) to ...
Phosphoglucomutase is absent in Trypanosoma brucei and redundantly substituted by phosphomannomutase and phospho-N-acetylglucosamine mutase
(Wiley Blackwell Publishing, Inc, 2012-07)
The enzymes phosphomannomutase (PMM), phospho-N-acetylglucosamine mutase (PAGM) and phosphoglucomutase (PGM) reversibly catalyze the transfer of phosphate between the C6 and C1 hydroxyl groups of mannose, N-acetylglucosamine ...
Effect of antibiotic administration on the structure of the larval microbiota of Genypterus chilensis in culture and the occurrence of genes coding for antimicrobial resistanceEfecto de la administración de antibióticos sobre la estructura de la microbiota larval de Genypterus chilensis en cultivo y la ocurrencia de genes que codifican para la resistencia a antimicrobianos
(2020)
The cultivation of Genypterus chilensis is currently considered a priority in national aquaculture and is within the Chilean Aquaculture Diversification Program (PDACh). But low larval survival rates have led to the need ...
Response from Varani et al. to “Comment on ‘the IS6 family, a clinically important group of insertion sequences including IS26’ by Ruth M. Hall”
(2022-12-01)
The IS6 family of insertion sequences is a large but coherent group which was originally named to avoid confusion between a number of identical or nearly identical IS that were identified at about the same time and given ...
Neutrophil-derived microvesicles enter cartilage and protect the joint in inflammatory arthritis
(2015-11-25)
Microvesicles (MVs) are emerging as a new mechanism of intercellular communication by transferring cellular lipid and protein components to target cells, yet their function in disease is only now being explored. We found ...
Synthesis and Biological Activity of Fluorinated Analogues of the DAF-12 Receptor Antagonist 24-Hydroxy-4-cholen-3-one
(Elsevier Science Inc, 2019-07)
The DAF-12 receptor is a ligand-activated transcription factor that in its ligand-bound form allows the expression of target genes needed to support the reproductive life cycle of the free-living nematode Caenorhabditis ...
Terapia génica en el manejo de las distrofias retinianas
(Universidad de La Salle. Facultad de Ciencias de la Salud. Optometría, 2017)
StarD7 gene expression in trophoblast cells: Contribution of SF-1 and Wnt-β-catenin signaling
(Endocrine Society, 2011-08)
Steroidogenic acute regulatory protein-related lipid transfer domain containing 7 (StarD7) is a poorly characterized member of the steroidogenic acute regulatory protein-related lipid transfer proteins, up-regulated in ...