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Quantitative structure-activity relationships for a series of inhibitors of cruzain from Trypanosoma cruzi: Molecular modeling, CoMFA and CoMSIA studies
(ELSEVIER SCIENCE INC, 2009)
Human parasitic diseases are the foremost threat to human health and welfare around the world. Trypanosomiasis is a very serious infectious disease against which the currently available drugs are limited and not effective. ...
The quantitative structure–insecticidal activity relationships from plant derived compounds against chikungunya and zika aedes aegypti (Diptera:Culicidae) vector
(2018-01-01)
The insecticidal activity of a series of 62 plant derivedmolecules against the chikungunya, dengue and zika vector,
the Aedes aegypti (Diptera:Culicidae) mosquito, is subjected to a Quantitative Structure–Activity ...
Uso de ferramentas in sílico de substâncias utilizadas no tratamento da doença de AlzheimerUso de ferramentas in sílico para a previsão da atividade biológica de compostos para fins terapêuticos
(Universidade Federal de Sergipe - Pró-reitoria de Pós-Graduação e Pesquisa - Coordenação de Pesquisa, 2022)
Three-dimensional quantitative structure-activity relationships for a large series of potent antitubercular agents
(BENTHAM SCIENCE PUBL LTD, 2008)
Comparative molecular field analysis (CoMFA) studies were conducted on a series of 100 isoniazid derivatives as anti-tuberculosis agents using two receptor-independent structural data set alignment strategies: (1) rigid-body ...
2D Quantitative structure–activity relationship studies on a series of cholesteryl ester transfer protein inhibitors
(2007)
Coronary heart disease (CHD) is one of the major causes of human death. The most successful therapeutic approach available is based on the reduction of low density-lipoprotein cholesterol (LDL-C). However, it is believed ...
Quantitatively relating cosmic rays intensities from solar activity parameters based on structural equation modeling
(Cartagena de Indias, 2023-03-06)
Cosmic rays measured through neutron monitors on Earth’s surface have a strong correlation with the number of sunspots on the
solar photosphere. Other indices that affect the dynamics of the heliosphere and distortions ...
Influence of spatial information coding into 2D and 3D descriptors for QSAR modelling purposesInfluência da codificação de informações espaciais em descritores 2D e 3D para fins de modelagem QSAR
(Universidade Federal de LavrasPrograma de Pós-graduação em AgroquímicaUFLAbrasilDepartamento de Química, 2023)
N -haloacetyl phenothiazines and derivatives: Preparation, characterization and structure-activity relationship for antifungal activity
(Elsevier, 2017-12)
A serie of N-acetyl phenothiazines and related compounds was synthesized by means of the acetylation reaction of the corresponding phenothiazine with the appropriate reagent using microwave irradiation. Structural elucidation ...