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Estudo químico de Jatropha curcas e de Jatropha gossypifolia nativas e cultivadas: avaliação de ciclopeptídeos em função de habitat e hábito : prospecção e atividade biológica
(Universidade Estadual Paulista (Unesp), 2009-02-16)
Este projeto é parte do projeto temático Conservation and Sustainable Use of the Plant Diversity from Cerrado and Atlantic Forest: Chemical Diversity and Prospecting for Potencial Drugs – Biota/FAPESP e descreve o isolamento, ...
Modificação covalente de peptideos antimicrobianos e anticancerigenos para a melhoria de suas propriedades farmacológicas
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Química - PPGQCâmpus São Carlos, 2019-08-16)
Following the information obtained by a rational design study, cyclic and dimeric helical stabilized analogues of the peptide Cm-p5 were synthetized. The cyclic monomer showed an increased activity in vitro ...
Peptídeos cíclicos em espécies do semiárido brasileiro e uma cultivada: caracterização e atividade biológica
(Universidade Estadual Paulista (UNESP), 2014)
Peptídeos cíclicos em espécies do semiárido brasileiro e uma cultivada: caracterização e atividade biológica
(Universidade Estadual Paulista (Unesp), 2014)
Autoantibodies as predictors of biological therapy for early rheumatoid arthritis
(MEDFARMA-EDICOES MEDICAS, LDA, 2010)
Introduction: The association between serological markers with the need of biological therapy for early rheumatoid arthritis (ERA) is not known, with few available data addressing this question. Objectives: To prospectively ...
Differential gene expression of peripheral blood mononuclear cells from rheumatoid arthritis patients may discriminate immunogenetic, pathogenic and treatment features
(WILEY-BLACKWELL PUBLISHING, INC, 2009)
This study aimed to evaluate the association between the differential gene expression profiling of peripheral blood mononuclear cells of rheumatoid arthritis patients with their immunogenetic (human leucocyte antigen ...
Multicomponent reactions in the discovery of organocatalysts and the diversification of organocatalytic approaches
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Química - PPGQCâmpus São Carlos, 2015-06-19)
This thesis reports the development of multicomponent approaches directed to specific objectives: a) the discovery of new and efficient peptide-based catalyst for asymmetric
transformations and b) the synthesis of ...
Assessment of the correlation between the activity of anti-cyclic citrullinated peptide IgG, topoisomerase I, and centromere proteins in Mexican patients with progressive systemic sclerosis
(2009)
Objective: To evaluate sera titers for antibodies anti-cyclic citrullinated peptide and their correlation against sera levels of anti-topoisomerase I and anti-centromere antibodies in Mexican patients with systemic sclerosis. ...
Assessment of the correlation between the activity of anti-cyclic citrullinated peptide IgG, topoisomerase I, and centromere proteins in Mexican patients with progressive systemic sclerosis
(2009)
Objective: To evaluate sera titers for antibodies anti-cyclic citrullinated peptide and their correlation against sera levels of anti-topoisomerase I and anti-centromere antibodies in Mexican patients with systemic sclerosis. ...
Dynamics and Conformational Studies of TOAC Spin Labeled Analogues of Ctx(Ile21)-Ha Peptide from Hypsiboas albopunctatus
(2013-04-09)
Antimicrobial peptides (AMPs) isolated from several organisms have been receiving much attention due to some specific features that allow them to interact with, bind to, and disrupt cell membranes. The aim of this paper ...