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Double-layered rotavirus-like particles are efficient carriers to elicit strong CTL responses to delivered heterologous antigens
(Elsevier, 2014-07)
The first 92 amino acids of VP2 of rotavirus are dispensable for VLP assembly and can be replaced by heterologous reporter proteins without affecting either self-assembly of chimeric VP2 or the interaction with VP6 to ...
Double-layered rotavirus-like particles are efficient carriers to elicit strong CTL responses to delivered heterologous antigens
(Elsevier, 2014-11)
The first 92 amino acids of VP2 of rotavirus are dispensable for VLP assembly and can be replaced by heterologous reporter proteins without affecting either self-assembly of chimeric VP2 or the interaction with VP6 to ...
Potenciais vacinas e marcadores de diagnóstico para toxoplasmose baseados em peptídeos quiméricos
(BrasilUFRNPROGRAMA DE PÓS-GRADUAÇÃO EM BIOQUÍMICA, 2018-03-28)
Toxoplasmosis is a zoonotic worldwide disease caused by the protozoan Toxoplasma gondii (T. gondii), which can infect several warm-blooded animals, including humans. The most severe symptoms are usually observed in ...
Production of chimeric embryos by aggregation of bovine egfp eight-cell stage blastomeres with two-cell fused and asynchronic embryos
(Elsevier Science Inc, 2013-06)
Embryo disaggregation allows the production of two to four identical offspring from a single cow embryo. In addition, embryo complementation has become the technique of choice to demonstrate the totipotency of embryonic ...
Chimeric structure of plant malic enzyme family: Different evolutionary scenarios for NAD- and NADP-dependent isoforms
(Frontiers Media, 2018-05)
Malic enzyme (ME) comprises a family of proteins with multiple isoforms located in different compartments of eukaryotic cells. In plants, cytosolic and plastidic enzymes share several characteristics such as NADP specificity ...
Chimeric protein designed by genome-scale immunoinformatics enhances serodiagnosis of bovine neosporosis
(Universidade Federal de Minas GeraisBrasilCOLTEC - COLEGIO TECNICOUFMG, 2020)
A neosporose tornou-se uma preocupação, uma vez que está associada ao aborto em bovinos. Atualmente, o diagnóstico in situ é determinado por meio de anamnese, avaliação da história e percepção dos sinais clínicos do rebanho. ...
Produção e avaliação de duas proteínas quiméricas - PQ10 e PQ20 - quanto à imunogenicidade e uso em imunodiagnóstico para Leishmaniose visceral canina
(Universidade Federal de Minas GeraisUFMG, 2014-02-17)
Visceral leishmaniasis is the most severe form among leishmaniasis. The zoonotic disease, caused by Leishmania infantum, represents 20 % of the world's human visceral leishmaniasis with increasing incidence in urban areas ...