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Anti-Candida targets and cytotoxicity of casuarinin isolated from Plinia cauliflora leaves in a bioactivity-guided study
(2013-07-01)
In addition to the bio-guided investigation of the antifungal activity of Plinia cauliflora leaves against different Candida species, the major aim of the present study was the search for targets on the fungal cell. The ...
Study of bioactive molecules of three cactaceae (Stenocereus pruinosus, Pachycereus weberi and Escontria Chiotilla) and their betalaina extraction in aqueous two-phase systems
Mexico has a great diversity of cacti, however, many of their fruits have not been studied in greater depth. Several bioactive compounds available in cacti juices extract have demonstrated nutraceutical properties. Two ...
Phenolic Compounds in Chilean Mistletoe (Quintral, Tristerix tetrandus) Analyzed by UHPLC–Q/Orbitrap/MS/MS and Its Antioxidant Properties
(MDPI AG, 2016)
Mass spectrometry has become a method of choice to characterize bioactive compounds in biological samples because of its sensitivity and selectivity. Hybrid ultra-HPLC hyphenated with Orbitrap mass analyzer is an innovative ...
Development of an effect-directed analysis via high-performance thin-layer chromatography-bioassay-mass spectrometry (HPTLC-bioassay-MS) platform for identification of bioactive compounds in cherimoya fruit (Annona chirimola Mill.)Implementación de una plataforma analítica HPTLC-bioensayo-MS de efecto dirigido para la identificación de compuestos bioactivos en chirimoya (Annona cherimola Mill.)
(2019)
Annona cherimola Mill. is a small tree cultivated in several countries including Chile. This tree produces a fruit called cherimoya, a good tasting fruit used in traditional medicine. Some beneficial biological activities ...
Bone regeneration mediated by a bioactive and biodegradable extracellular matrix-like hydrogel based on elastin-like recombinamers
(Mary Ann Liebert, 2017-12)
The morbidity of bone fractures and defects is steadily increasing due to changes in the age pyramid. As such, novel biomaterials that are able to promote the healing and regeneration of injured bones are needed to overcome ...
Incorporation of beads into oral films for buccal and oral delivery of bioactive molecules
(Elsevier, 2018-08-09)
The association of alginate beads and guar-gum films in a single delivery system was idealized to promote a more effective buccal and oral delivery of bioactive molecules. A response surface method (experimental design ...
Caracterização inicial dos extratos de Tephrosia toxicaria (Sw.) Pers. quanto a atividade leishmanicida e toxicidade
(Universidade Federal do Rio Grande do NorteBrasilUFRNBiomedicinaCentro de Biociências, 2022-02-15)
Leishmaniasis is a complex zoonosis caused by protozoa of the genus Leishmania, vectored by sandflies that affect humans and other vertebrates. Of the available therapeutic options, pentavalent antimonials are the first-choice ...