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Tumor-infiltrating CD4+ and CD8+ lymphocytes and macrophages are associated with prognostic factors in triple-negative canine mammary complex type carcinoma
(2019-10-01)
This study aimed to evaluate the association of CD3+, CD4+, and CD8+ T cells and tumor-infiltrating macrophages (TIMs) with the clinical parameters of female dogs harboring mammary gland tumors. Thirty female dogs affected ...
Effects of propolis and phenolic acids on triple-negative breast cancer cell lines: Potential involvement of epigenetic mechanisms
(2020-03-02)
Triple-negative breast cancer is an aggressive disease frequently associated with resistance to chemotherapy. Evidence supports that small molecules showing DNA methyltransferase inhibitory activity (DNMTi) are important ...
Evaluación de los riesgos mecánicos en el área de maquinado de una empresa metal mecánica
(2022)
In order to help the company to reduce and prevent the risk index that exists in the machining area, taking as an important point the mechanical presses, which if a bad operation is used in these machines cause blows, cuts, ...
Toward a cleaner and more sustainable world: A framework to develop and improve waste management through organizations, governments and academia
(2022-04-01)
Waste production is expected to reach 3.40 billion tons annually in 2050. To decrease its negative impacts on the environment generated by human activities, waste management (WM) aims to increase the products life cycle ...
Possible Relationship between Basal-Like Breast Carcinoma and Age
(KargerBaselSuíça, 2009)
Therapeutic opportunities for PLK1 inhibitors: Spotlight on BRCA1-deficiency and triple negative breast cancers
(Elsevier Science, 2020-05)
Polo-Like Kinases (PLKs) are central players of mitotic progression in Eukaryotes. Given the intimate relationship between cell cycle progression and cancer development, PLKs in general and PLK1 in particular have been ...
Humanin promotes tumor progression in experimental triple negative breast cancer
(Nature Publishing Group, 2020-12)
Humanin (HN) is a mitochondrial-derived peptide with cytoprotective effect in many tissues. Administration of HN analogs has been proposed as therapeutic approach for degenerative diseases. Although HN has been shown to ...
Stress hormones reduce the efficacy of paclitaxel in triple negative breast cancer through induction of DNA damage
(Nature Publishing Group, 2015-04)
Background: The mechanisms by which stress hormones impact triple-negative breast cancer (TNBC) etiology and treatment are unclear. We have previously shown that stress hormones, cortisol, and catecholamines induce rapid ...