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Cholestasis-induced fibrosis is reduced by interferon α-2a and is associated with elevated liver metalloprotease activity
(2000)
Background/Aim: Several drugs have been tested for the treatment of hepatic cirrhosis induced by various etiologic agents. Although interferon (IFN)α-2a has mostly been used to treat viral hepatitis, its anti-fibrogenic ...
Neutralization of myotoxic phospholipases A2 from the venom of the snake Bothrops asper by monoclonal antibodies
(1992)
The neutralization of two myotoxic phospholipases A2 from the venom of Bothrops asper, myotoxins I and II, by two murine monoclonal antibodies is reported. The monoclonal antibodies, MAb-3 and Mab-4, recognize different ...
Medicinal plants with inhibitory properties against snake venoms
(2005)
Envenomations due to snake bites are commonly treated by parenteral administration of horse or
sheep-derived polyclonal antivenoms aimed at the neutralization of toxins. However, despite the widespread
success of this ...
Does native Trypanosoma cruzi calreticulin mediate growth inhibition of a mammary tumor during infection?
(2016)
Background: For several decades now an antagonism between Trypanosoma cruzi infection and tumor development has been detected. The molecular basis of this phenomenon remained basically unknown until our proposal that T. ...
Purification and partial characterization of a midgut membrane-bound alpha-glucosidase from Quesada gigas (Hemiptera: Cicadidae)
(ELSEVIER SCIENCE INC, 2010)
Adults of Quesada gigas (Hemiptera: Cicadidae) have a major alpha-glucosidase bound to the perimicrovillar membranes, which are lipoprotein membranes that surround the midgut cell microvilli in Hemiptera and Thysanoptera. ...
Recombinant expression, purification, and functional analysis of two novel cystatins from sugarcane (Saccharum officinarum)
(Elsevier B.V., 2006-06-01)
Phytocystatins are cysteine proteinase inhibitors from plants implicated in the endogenous regulation of protein turnover, programmed cell death, and in defense mechanisms against pathogens. To date, only few cystatin genes ...
The involvement of the spleen during chronic phase of Schistosoma mansoni infection in galectin-3(-/-) mice
(F HERNANDEZMURCIA, 2012)
Schistosoma mansoni synthesizes glycoconjugates which interact with galectin-3, eliciting an intense humoral immune response. Moreover, it was demonstrated that galectin-3 regulates B cell differentiation into plasma cells. ...
Galectin-8 promotes regulatory T-cell differentiation by modulating IL-2 and TGFβ signaling
(Australian Society for Immunology, 2016-02)
Galectins (Gals) have emerged as potent immunoregulatory molecules that control chronic inflammation through distinct mechanisms. Gal-8, a tandem-repeat type Gal with unique preference for α2,3-sialylated glycans, is ...
Distribution and hydrolytic enzyme characteristics of Candida albicans strains isolated from diabetic patients and their non-diabetic consorts
(Wiley-Blackwell Publishing, Inc, 2009-12-01)
Introduction:The aim of this study was to investigate the oral colonization profile of Candida albicans strains isolated from diabetic patients and their non-diabetic consorts. In addition hydrolytic enzyme activity of ...