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Estrutura e gestão dos canais de distribuição na indústria de alimentos para cães e gatos (petfood)
(Universidade Federal de São CarlosBRUFSCarPrograma de Pós-Graduação em Engenharia de Produção - PPGEP, 2006-11-29)
The pet, especially dogs and cats, possess a growing participation in home
living and in the human and social coexistence, linking intensely with their owners and
providing moments of pleasure and happiness. The market of ...
Interaction of local anesthetics with a peptide encompassing the IV/S4-S5 linker of the Na+ channel
(Elsevier Science BvAmsterdamHolanda, 2006)
Searching for New Leads to Treat Epilepsy: Target-Based Virtual Screening for the Discovery of Anticonvulsant Agents
(American Chemical Society, 2018-07)
The purpose of this investigation is to contribute to the development of new anticonvulsant drugs to treat patients with refractory epilepsy. We applied a virtual screening protocol that involved the search into molecular ...
A novel μ-conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors
(2012)
BACKGROUND AND PURPOSE The μ-conopeptide family is defined by its ability to block voltage-gated sodium channels (VGSCs), a property that can be used for the development of myorelaxants and analgesics. We characterized the ...
Puroindoline-a and α1-purothionin form ion channels in giant liposomes but exert different toxic actions on murine cells
(2006)
Puroindoline-a (PIN-a) and α1-purothionin (α1-PTH), isolated from wheat endosperm of Triticum aestivum sp., have been suggested to play a role in plant defence mechanisms against phytopathogenic organisms. We investigated ...
Histochemical differences in the responses of predominantly fast-twitch glycolytic muscle and slow-twitch oxidative muscle to veratrine
(Pergamon-elsevier Science LtdOxfordInglaterra, 2002)
Sequence and structure-activity relationship of a scorpion venom toxin with nitrergic activity in rabbit corpus cavernosum
(Federation Amer Soc Exp BiolBethesdaEUA, 2003)
Interaction between brain L-type calcium channels and alpha(2)-adrenoceptors in the inhibition of sodium appetite
(Elsevier B.V., 2002-03-22)
Calcium channels mediate the actions of many drugs. The present work investigated whether diltiazem, an L-type calcium channel blocker, alters the inhibition of sodium appetite induced by noradrenaline and the alpha(2)-a ...
Structural analysis of Tityus serrulatus Ts1 neurotoxin at atomic resolution: insights into interactions with Na+ channels
(Blackwell MunksgaardCopenhagenDinamarca, 2003)