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Caracterização funcional do LOPAP (ativador de protrombina da lagarta Lanomia oblíqua)
(Universidade Federal de São Paulo (UNIFESP), 2002)
A lagarta Lonomia obliqua é encontrada no sul do Brasil, e o contato da pele humana com suas cerdas, em forma de "espinhos", causa entre outros sintomas, uma severa síndrome hemorrágica devido a coagulopatia de consumo, ...
Avaliação do potencial condroprotetor da molécula r losac em modelo inflamatório induzidos pela interleucina 1beta
(Universidade Federal de São Paulo (UNIFESP), 2016-12-30)
Background: Osteoarthritis is an articular disease more prevalent, resulting in the progressive deterioration of the articular cartilage, mediated by proinflammatory pathways of the innate immunity and the production of ...
Effects of Lopap on Human Endothelial Cells and Platelets
(Karger, 2001-05)
Severe consumption coagulopathy has been detected in rats after Lopap (a prothrombin activator from Lonomia obliqua caterpillar bristles) infusion and in humans after accidental contact with L. obliqua bristles. However, ...
Coagulação sanguínea: ação de substratos e de inibidores peptídicos
(Universidade Federal de São Paulo (UNIFESP), 2003)
BuXI, o inibidor do tipo Kunitz isolado das sementes de B. ungulata inativa fator Xa, calicreina plasmatica humana, tripsina e o LOPAP, ativador de protrombina isolado das cerdas da lagarta Lonomia obliqua. BvTI, isolado ...
Reversal of the anticoagulant and anti-hemostatic effect of low molecular weight heparin by direct prothrombin activation
(Associação Brasileira de Divulgação Científica (ABRADIC), 2012-10-01)
Lopap, found in the bristles of Lonomia obliqua caterpillar, is the first exogenous prothrombin activator that shows serine protease-like activity, independent of prothrombinase components and unique lipocalin reported to ...
Reversal of the anticoagulant and anti-hemostatic effect of low molecular weight heparin by direct prothrombin activation
(Associação Brasileira de Divulgação Científica (ABRADIC), 2012-10-01)
Lopap, found in the bristles of Lonomia obliqua caterpillar, is the first exogenous prothrombin activator that shows serine protease-like activity, independent of prothrombinase components and unique lipocalin reported to ...