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Calorimetric study of the antibacterial activity of sodium n-alkylsulfates on the metabolism of Chromobacterium violaceum
(Sociedade Brasileira de Química, 2005)
COVID-19 treatment: Much research and testing, but far, few magic bullets against SARS-CoV-2 coronavirus
The new virus of the of β-Coronaviruses genus, SARS-CoV-2, is the causative agent of coronavirus disease2019 (COVID-19) and is winning a proverbial chess match against all players simultaneous, including
physicians, ...
Effect of ANITVNITV peptide fusion on the bioactivity and pharmacokinetics of human IFN-α2b and a hyper-N-glycosylated variant
(Elsevier Science, 2019-09)
Different strategies have been developed and successfully applied to biotherapeutics in order to improve their in vivo efficacy. The genetic fusion to natural or synthetic glycosylated peptides constitutes a promising ...
Bioprospecção e purificação de substâncias bioativas produzidas por Streptomyces tubercidicus, endofítico isolado de Solanum lycocarpum St. Hill (Lobeira) do cerrado de São Carlos-SP
(Universidade Federal de São CarlosBRUFSCarPrograma de Pós-Graduação em Biotecnologia - PPGBiotec, 2009-12-11)
The need for new and useful compounds to provide assistance and relief in all aspects of human condition is ever-growing. Drug resistance in bacteria, the appearance of life-threatening viruses, and the increase in the ...
Amaranth peptides with antithrombotic activity released by simulated gastrointestinal digestion
(Elsevier, 2016-01)
Amaranth protein isolate was obtained and subjected to simulated gastrointestinal digestion to evaluate its potential antithrombotic activity. The protein isolate did not present fibrin clotting inhibition at the concentrations ...
Purification and characterization of a novel thermostable papain inhibitor from Moringa oleifera with antimicrobial and anticoagulant properties
(Multidisciplinary Digital Publishing Institute, 2021-04)
Plant cystatins (or phytocystatins) comprise a large superfamily of natural bioactive small proteins that typically act as protein inhibitors of papain-like cysteine proteases. In this report, we present the purification ...
Anti-Candida targets and cytotoxicity of casuarinin isolated from Plinia cauliflora leaves in a bioactivity-guided study
(2013-07-01)
In addition to the bio-guided investigation of the antifungal activity of Plinia cauliflora leaves against different Candida species, the major aim of the present study was the search for targets on the fungal cell. The ...