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Arachidonic acid in adipose tissue is associated with nonfatal acute myocardial infarction in the Central Valley of Costa Rica
(2004-11)
Arachidonic acid (AA), a precursor of prothrombotic eicosanoids, is potentially atherogenic, but epidemiologic data are scarce. We evaluated the hypothesis that increased AA in adipose tissue is associated with increased ...
Inhibitors of cytochrome P-450-dependent arachidonic acid metabolism
(1988)
A new generation of heteroatom analogs of arachidonic acid are documented as powerful and selective inhibitors of the cytochrome P-450-dependent arachidonic acid oxygenase reaction (IC50, 5-10 μm) with little effect on ...
Adipose tissue arachidonic acid and the metabolic syndrome in Costa Rican adults
(2007)
Arachidonic acid, a precursor to a series of inflammatory mediators, may contribute to the development of insulin resistance. We examined the association between adipose tissue arachidonic acid and the metabolic syndrome ...
Plasma Arachidonic Acid Influences Insulin-Stimulated Glucose Uptake in Healthy Adult Women
(Karger, 2007)
Background: Fatty acids can modulate lipid metabolism,
this is related to insulin resistance (IR). This study evaluated
the relationship of plasma fatty acid profile with IR, fuel oxidative
metabolism and plasma lipid ...
Arachidonic and docosahexaenoic acids are biosynthesized from their 18-carbon precursors in human infants
(National Academy of Sciences, 1996)
It is becoming clear that an adequate level of lung-chain highly unsaturated fatty acids in the nervous system is required for optimal function and development; however, the ability of infants to biosynthesize long-chain ...
Arachidonic acid actions on functional integrity and attenuation of the negative effects of palmitic acid in a clonal pancreatic beta-cell line
(PORTLAND PRESS LTD, 2011)
Chronic exposure of pancreatic beta-cells to saturated non-esterified fatty acids can lead to inhibition of insulin secretion and apoptosis. Several previous studies have demonstrated that saturated fatty acids such as PA ...
Endothelial dysfunction in DOCA-salt hypertension - Possible involvement of prostaglandin endoperoxides
(Elsevier B.V., 1999-03-01)
The effects of the arachidonic acid metabolism inhibitors on the acetylcholine responses of aortae from control (CR) and deoxycorticosterone acetate (DOCA)-salt hypertensive (HR) rats were investigated. The acetylcholine ...